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Literature summary for 2.7.11.23 extracted from

  • Prelich, G.
    RNA polymerase II carboxy-terminal domain kinases: emerging clues to their function (2002), Eukaryot. Cell, 1, 153-162.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] Drosophila sp. (in: flies) the CTD is essential for viability, although mutants with deletions that remove approximately half of the repeats are still viable ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
-
?
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] Mus musculus the CTD is essential for viability, although mutants with deletions that remove approximately half of the repeats are still viable ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
-
?
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] Saccharomyces cerevisiae the CTD is essential for viability, although mutants with deletions that remove approximately half of the repeats are still viable ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
-
?

Organism

Organism UniProt Comment Textmining
Drosophila sp. (in: flies)
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Mus musculus
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-
-
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] the CTD is essential for viability, although mutants with deletions that remove approximately half of the repeats are still viable Drosophila sp. (in: flies) ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
-
?
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] the CTD is essential for viability, although mutants with deletions that remove approximately half of the repeats are still viable Mus musculus ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
-
?
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] the CTD is essential for viability, although mutants with deletions that remove approximately half of the repeats are still viable Saccharomyces cerevisiae ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
-
?