Activating Compound | Comment | Organism | Structure |
---|---|---|---|
p35 | - |
Mus musculus | |
p35 | - |
Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | the p25/Cdk5 complex is an important mediator of dopamine and glutamate neurotoxicity associated to Huntigton's disease | Mus musculus |
medicine | the p25/Cdk5 complex is an important mediator of dopamine and glutamate neurotoxicity associated to Huntigton's disease | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
roscovitine | 0.02 mM, potent Cdk5 inhibitor | Homo sapiens | |
roscovitine | 0.02 mM, potent Cdk5 inhibitor | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q00535 | - |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
corpus striatum | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + histone 1 | - |
Mus musculus | ADP + phosphorylated histone 1 | - |
? | |
ATP + histone 1 | - |
Homo sapiens | ADP + phosphorylated histone 1 | - |
? | |
ATP + huntingtin | - |
Mus musculus | ADP + phosphorylated huntingtin | - |
? | |
ATP + huntingtin | - |
Homo sapiens | ADP + phosphorylated huntingtin | - |
? | |
ATP + tau protein | - |
Mus musculus | ADP + phosphorylated tau protein | - |
? | |
ATP + tau protein | - |
Homo sapiens | ADP + phosphorylated tau protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cdk5 | - |
Mus musculus |
Cdk5 | - |
Homo sapiens |
cyclin-dependent kinase 5 | - |
Mus musculus |
cyclin-dependent kinase 5 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cyclin | - |
Mus musculus | |
cyclin | - |
Homo sapiens |