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Literature summary for 2.7.11.22 extracted from

  • Hahn, C.M.; Kleinholz, H.; Koester, M.P.; Grieser, S.; Thelen, K.; Pollerberg, G.E.
    Role of cyclin-dependent kinase 5 and its activator P35 in local axon and growth cone stabilization (2005), Neuroscience, 134, 449-465.
    View publication on PubMed
Search for more literature for 2.7.11.22

Activating Compound

Activating Compound Comment Organism Structure
p35 regulatory subunit of Cdk5 Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
roscovitine
-
 Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Gallus gallus 5737
-
membrane
-
 Gallus gallus 16020
-
additional information subcellular localization of Cdk5-p35 Gallus gallus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + MAP1B Gallus gallus reaction in growth cones is important for stability of microtubules ADP + phosphorylated MAP1B
-
 ?
additional information Gallus gallus Cdk5 is crucial for stability of axons and growth cones in retina, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
egg fertilized Gallus gallus
-
additional information Cdk5 is crucial for stability of axons and growth cones in retina Gallus gallus
-
retina embryonic retinal cell culture, developmental expression analysis of Cdk5-p35, Cdk5-p35 localize in the stable region of turning growth cones in developing retina Gallus gallus
-
zygote fertilized eggs Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + MAP1B reaction in growth cones is important for stability of microtubules Gallus gallus ADP + phosphorylated MAP1B
-
 ?
ATP + MAP1B type 1 phosphorylation in the mab1E11 recognition site Gallus gallus ADP + phosphorylated MAP1B
-
 ?
additional information Cdk5 is crucial for stability of axons and growth cones in retina, overview Gallus gallus ?
-
 ?

Synonyms

Synonyms Comment Organism
Cdk5
-
 Gallus gallus
cyclin-dependent kinase 5
-
 Gallus gallus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Gallus gallus