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Literature summary for 2.7.11.18 extracted from

  • Olson, N.J.; Pearson, R.B.; Needleman, D.S.; Hurwitz, M.Y.; Kemp, B.E.; Means, A.R.
    Regulatory and structural motifs of chicken gizzard myosin light chain kinase (1990), Proc. Natl. Acad. Sci. USA, 87, 2284-2288.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.18

Inhibitors

Inhibitors Comment Organism Structure
additional information autoregulatory domain extends from Asn780 to Arg808. The peptide Leu774 to Ser787 does not inhibit smMLCK, peptides of similar or shorter length from the pseudosubstrate region, Ser787 to Val807, are potent inhibitors Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin light chain Gallus gallus
-
 ADP + phosphorylated myosin light chain
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus P11799
-
-
Gallus gallus P11799 regulatory and structural motifs
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin light chain
-
 Gallus gallus ADP + phosphorylated myosin light chain
-
 ?

Synonyms

Synonyms Comment Organism
myosin light chain kinase
-
 Gallus gallus
myosin light chain kinase, smooth muscle and non-muscle isozymes
-
 Gallus gallus