Application | Comment | Organism |
---|---|---|
medicine | blocking CaMKII or CaMKII-mediated signaling may offer a novel therapeutic target for the treatment of neuropathic pain | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-[N-(2-hydroxyethyl)-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine | KN93 | Mus musculus | |
Trifluoperazine | - |
Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | Mus musculus | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
spinal nerve | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
Mus musculus | ADP + a phosphoprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ca2+/calmodulin-dependent protein kinase II | - |
Mus musculus |
CaMKII | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | spinal nerve L5/L6 ligation, SNL, is found to increase the spinal activity of CaMKII on the ipsilateral side, blocked by KN93 | up |