Activating Compound | Comment | Organism | Structure |
---|---|---|---|
light | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | GRK1-dependent phosphorylation of cone opsins and binding to cone arrestin leads to association of cone arrestins to the membrane in a light-dependent manner | Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + M opsin | Mus musculus | M opsin binds to cone arrestin during cone phototransduction in the retina | ADP + phosphorylated m opsin | - |
? | |
ATP + M opsin | Mus musculus C57/BL6J | M opsin binds to cone arrestin during cone phototransduction in the retina | ADP + phosphorylated m opsin | - |
? | |
ATP + S opsin | Mus musculus | S opsin binds to cone arrestin during cone phototransduction in the retina | ADP + phosphorylated S opsin | - |
? | |
ATP + S opsin | Mus musculus C57/BL6J | S opsin binds to cone arrestin during cone phototransduction in the retina | ADP + phosphorylated S opsin | - |
? | |
additional information | Mus musculus | analysis of the deactivation of the cone phototransduction cascade in mouse retina and the role of GRK1, GRK1-dependent phosphorylation of cone opsins and binding to cone arrestin leads to association of cone arrestins to the membrane in a light-dependent manner | ? | - |
? | |
additional information | Mus musculus C57/BL6J | analysis of the deactivation of the cone phototransduction cascade in mouse retina and the role of GRK1, GRK1-dependent phosphorylation of cone opsins and binding to cone arrestin leads to association of cone arrestins to the membrane in a light-dependent manner | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
C57BL/6J mice | - |
Mus musculus C57/BL6J | - |
C57BL/6J mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
photoreceptor | S and M cone photoreceptors, expression of GRK1 | Mus musculus | - |
retina | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + M cone opsin | light-dependent, multi-site phosphorylation | Mus musculus | ADP + phosphorylated M cone opsin | - |
? | |
ATP + M cone opsin | light-dependent, multi-site phosphorylation | Mus musculus C57/BL6J | ADP + phosphorylated M cone opsin | - |
? | |
ATP + M opsin | M opsin binds to cone arrestin during cone phototransduction in the retina | Mus musculus | ADP + phosphorylated m opsin | - |
? | |
ATP + M opsin | M opsin binds to cone arrestin during cone phototransduction in the retina | Mus musculus C57/BL6J | ADP + phosphorylated m opsin | - |
? | |
ATP + S cone opsin | light-dependent, multi-site phosphorylation | Mus musculus | ADP + phosphorylated S cone opsin | - |
? | |
ATP + S cone opsin | light-dependent, multi-site phosphorylation | Mus musculus C57/BL6J | ADP + phosphorylated S cone opsin | - |
? | |
ATP + S opsin | S opsin binds to cone arrestin during cone phototransduction in the retina | Mus musculus | ADP + phosphorylated S opsin | - |
? | |
ATP + S opsin | S opsin binds to cone arrestin during cone phototransduction in the retina | Mus musculus C57/BL6J | ADP + phosphorylated S opsin | - |
? | |
additional information | analysis of the deactivation of the cone phototransduction cascade in mouse retina and the role of GRK1, GRK1-dependent phosphorylation of cone opsins and binding to cone arrestin leads to association of cone arrestins to the membrane in a light-dependent manner | Mus musculus | ? | - |
? | |
additional information | analysis of the deactivation of the cone phototransduction cascade in mouse retina and the role of GRK1, GRK1-dependent phosphorylation of cone opsins and binding to cone arrestin leads to association of cone arrestins to the membrane in a light-dependent manner | Mus musculus C57/BL6J | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GPCR kinase 1 | - |
Mus musculus |
GRK1 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |