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Literature summary for 2.7.11.14 extracted from

  • Shi, G.W.; Chen, J.; Concepcion, F.; Motamedchaboki, K.; Marjoram, P.; Langen, R.
    Light causes phosphorylation of nonactivated visual pigments in intact mouse rod photoreceptor cells (2005), J. Biol. Chem., 280, 41184-41191.
    View publication on PubMed
Search for more literature for 2.7.11.14

Activating Compound

Activating Compound Comment Organism Structure
light stimulates rhodopsin activation by phosphorylation Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information construction of transgenic mouse photoreceptor cells overexpressing the human S opsin mutant K296E still show the trans-phosphorylation phenomenon and phosphorylation of nonactivated rhodopsin, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + rhodopsin Mus musculus the enzyme phosphorylates activated rhodopsin, light causes phosphorylation of nonactivated rhodopsin in intact rod photoreceptor cells ADP + phosphorhodopsin
-
 ?
additional information Mus musculus dark-adapted retina rhodopsin is also phosphorylated in transgenic photoreceptor cells overexpressing the human S opsin mutant K296E ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + rhodopsin = ADP + phosphorhodopsin molecular mechanism of trans-phosphorylation Mus musculus
a

Source Tissue

Source Tissue Comment Organism Textmining
photoreceptor
-
 Mus musculus
-
retina
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + rhodopsin
-
 Mus musculus ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin the enzyme phosphorylates activated rhodopsin, light causes phosphorylation of nonactivated rhodopsin in intact rod photoreceptor cells Mus musculus ADP + phosphorhodopsin
-
 ?
ATP + S opsin trans-phosphorylation is induced by activated rhodopsin Mus musculus ADP + phosphorylated S opsin
-
 ?
additional information dark-adapted retina rhodopsin is also phosphorylated in transgenic photoreceptor cells overexpressing the human S opsin mutant K296E Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
More the enzyme belongs to the G-protein coupled receptor kinase family Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus