Cloned (Comment) | Organism |
---|---|
isozyme UGT1A10, realtime expression analysis in healthy and malignant breast tissue samples from African American and Caucasian women, overview | Homo sapiens |
isozyme UGT2B7, realtime expression analysis in healthy and malignant breast tissue samples from African American and Caucasian women, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-D-glucuronate + 17beta-estradiol | Homo sapiens | - |
UDP + 17beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-D-glucuronate + acceptor | Homo sapiens | - |
UDP + acceptor beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-hydroxy-estrone | Homo sapiens | glucuronidation of 4-hydroxylated estrone is significantly reduced in breast carcinomas compared to healthy | UDP + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozyme UGT2B7 | - |
Homo sapiens | P36537 | isozyme UGT1A10; isozyme UGT1A10 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast | identification of isozyme UGT1A10 in non-malignant and malignant human breast tissues, UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT1A10 expression is significantly decreased in breast carcinomas in comparison to healthy, while among Caucasian women, overview | Homo sapiens | - |
breast | UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT2B7 is significantly decreased in breast carcinomas in comparison to healthy, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-D-glucuronate + 17beta-estradiol | - |
Homo sapiens | UDP + 17beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-D-glucuronate + 4-hydroxy-estrone | - |
Homo sapiens | UDP + ? | - |
? | |
UDP-D-glucuronate + acceptor | - |
Homo sapiens | UDP + acceptor beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-hydroxy-estrone | glucuronidation of 4-hydroxylated estrone is significantly reduced in breast carcinomas compared to healthy | Homo sapiens | UDP + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucuronosyltransferase 1A10 | - |
Homo sapiens |
UGT1A10 | - |
Homo sapiens |
UGT2B7 | - |
Homo sapiens |