Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | interleukin-6 or interleukin-8 significantly induce the expression of alpha1,3/4-fucosyltransferases, the amounts of sialyl-Lewisx and 6-sulfo-sialyl-Lewisx epitopes at the periphery of high molecular-mass proteins, including MUC4, are increased | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
gene FUT11, expression analysis in bronchial mucosa of cystic fibrosis patients | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-beta-L-fucose + NeuAcalpha(2,3)-Galbeta(1,4)-GlcNAc-R | Homo sapiens | sialyl-Lewisx terminal structure | GDP + NeuAcalpha(2,3)-Galbeta(1,4)[Fucalpha1-3]-GlcNAc-R | - |
? | |
GDP-beta-L-fucose + NeuAcalpha(2,3)-Galbeta(1,4)[SO3H-6]-GlcNAc-R | Homo sapiens | sialyl-Lewisx terminal structure | GDP + NeuAcalpha(2,3)-Galbeta(1,4)[Fucalpha1-3][SO3H-6]-GlcNAc-R | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
gene FUT11 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bronchial mucosa | from patients suffering from cystic fibrosis | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-beta-L-fucose + NeuAcalpha(2,3)-Galbeta(1,4)-GlcNAc-R | sialyl-Lewisx terminal structure | Homo sapiens | GDP + NeuAcalpha(2,3)-Galbeta(1,4)[Fucalpha1-3]-GlcNAc-R | - |
? | |
GDP-beta-L-fucose + NeuAcalpha(2,3)-Galbeta(1,4)[SO3H-6]-GlcNAc-R | sialyl-Lewisx terminal structure | Homo sapiens | GDP + NeuAcalpha(2,3)-Galbeta(1,4)[Fucalpha1-3][SO3H-6]-GlcNAc-R | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha1,3/4-fucosyltransferase | - |
Homo sapiens |
fucosyltransferase 11 | - |
Homo sapiens |
FUT11 | - |
Homo sapiens |