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Literature summary for 2.3.1.75 extracted from

  • Yen, C.L.; Monetti, M.; Burri, B.J.; Farese, R.V.
    The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters (2005), J. Lipid Res., 46, 1502-1511.
    View publication on PubMed
Search for more literature for 2.3.1.75

Protein Variants

Protein Variants Comment Organism
additional information the wax diester synthase activity of DGAT1 helps to explain the deficiency of type II wax diesters in the fur lipids of Dgat-/- mice Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1,2-hexadecandiol + palmitoyl-CoA Mus musculus
-
 ?
-
 ?
1-hexadecanol + palmitoyl-CoA Mus musculus
-
 CoA + hexadecylpalmitate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-hexadecandiol + palmitoyl-CoA
-
 Mus musculus ?
-
 ?
1-hexadecanol + palmitoyl-CoA
-
 Mus musculus CoA + hexadecylpalmitate
-
 ?
additional information DGAT1 is catalyzing the reactions of the monoacylglycerol transferase, EC 2.3.1.22, of the diacylglycerol transferase, EC 2.3.1.20, of the wax synthase, EC 2.3.1.75, and of the acyl-CoA:retinol acyltransferase, EC 2.3.1.76, DGAT2 catalyzes the wax ester synthase reaction, overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
acyl CoA:long-chain fatty alcohol O-acyltransferase
-
 Mus musculus
additional information cf. EC 2.3.1.20 Mus musculus
wax monoester synthase
-
 Mus musculus
wax synthase
-
 Mus musculus