Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.60 extracted from

  • Rowe, P.M.; Wright, L.S.; Siegel, F.L.
    Calmodulin N-methyltransferase. Partial purification and characterization (1986), J. Biol. Chem., 261, 7060-7069.
    View publication on PubMed
Search for more literature for 2.1.1.60

Activating Compound

Activating Compound Comment Organism Structure
dithiothreitol stimulates Rattus norvegicus
Triton X-100
-
 Rattus norvegicus

General Stability

General Stability Organism
Triton stabilizes during purification Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
additional information found at high levels in tissues with high levels of calmodulin, at low levels in tissues with low levels of calmodulin like liver, heart, skeletal muscle Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-
testis
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Storage Stability

Storage Stability Organism
-20°C, up to 2 weeks Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + calmodulin L-lysine highly specific Rattus norvegicus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine 3 mol of methyl per mol of calmodulin are incorporated into lysine 115 of des(methyl) calmodulin from Dictyostelium discoideum resulting in formation of 1 mol of trimethyllysine at the site normally methylated ?
S-adenosyl-L-methionine + calmodulin L-lysine Dictyostelium discoideum calmodulin Rattus norvegicus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine 3 mol of methyl per mol of calmodulin are incorporated into lysine 115 of des(methyl) calmodulin from Dictyostelium discoideum resulting in formation of 1 mol of trimethyllysine at the site normally methylated ?