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Literature summary for 2.1.1.60 extracted from

  • Murtaugh, T.J.; Rowe, P.M.; Vincent, P.L.; Wright, L.S.; Siegel, F.L.
    Posttranslational modification of calmodulin (1983), Methods Enzymol., 102, 158-170.
    View publication on PubMed
Search for more literature for 2.1.1.60

Activating Compound

Activating Compound Comment Organism Structure
Mg2+
-
 Rattus norvegicus
Mn2+ stimulation Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00001
-
 Calmodulin
-
 Rattus norvegicus
0.001
-
 S-adenosyl-L-methionine
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ activation Rattus norvegicus
Mn2+ stimulation Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + calmodulin L-lysine Rattus norvegicus posttranslational modification of calmodulin S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
-20°C Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information troponin C has low activity at very high troponin concentration Rattus norvegicus ?
-
 ?
S-adenosyl-L-methionine + calmodulin L-lysine highly specific Rattus norvegicus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
-
 ?
S-adenosyl-L-methionine + calmodulin L-lysine posttranslational modification of calmodulin Rattus norvegicus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Rattus norvegicus