Application | Comment | Organism |
---|---|---|
medicine | spermine oxidase is an important positive regulator of muscle fiber size whose expression is strongly downregulated by conditions that cause muscle atrophy. This reduction in spermine oxidase enables the atrophy process and represents a potential target for therapeutic intervention | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q99K82 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | - |
Mus musculus | - |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | reduced spermine oxidase expression may contribute to muscle atrophy during a variety of stress conditions, including immobilization, denervation, fasting, and aging | Mus musculus |
physiological function | spermine oxidase as an important positive regulator of muscle gene expression and fiber size | Mus musculus |