Crystallization (Comment) | Organism |
---|---|
mutant W335A/F336L, showing two similar, but not identical subunits. The cluster involved in conformation-switching is completely disrupted in one subunit, but remains partly associated in the other. Xanthine oxidase and oxidoreductase forms of the mutant are in equilibrium that greatly favors the oxidase form, but upon incubation with dithiothreitol equilibrium is partly shifted towards the oxidoreductase form | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
W335A/F336L | mutant oxidoreductase displaying xanthine oxidase activity | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P22985 | conversion of oxidoreductatse to oxidase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + NAD+ + H2O | - |
Rattus norvegicus | urate + NADH + H+ | - |
? |