Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | 100000 x g supernatant, cerebral cortex, liver | Homo sapiens | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + NAD+ + H2O | Homo sapiens | - |
urate + NADH | - |
r | |
xanthine + NAD+ + H2O | Oryctolagus cuniculus | - |
urate + NADH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
dehydrogenase activity predominant form | - |
Oryctolagus cuniculus | - |
rabbit | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Homo sapiens | - |
cerebellum | - |
Oryctolagus cuniculus | - |
cerebellum | high rate of dehydrogenase activity | Homo sapiens | - |
cerebral cortex | - |
Oryctolagus cuniculus | - |
cerebral cortex | high rate of dehydrogenase activity | Homo sapiens | - |
heart | - |
Oryctolagus cuniculus | - |
heart | high rate of dehydrogenase activity | Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | high oxidase and reductase activities at nearly the same rates | Homo sapiens | - |
liver | high oxidase and reductase activities at nearly the same rates | Oryctolagus cuniculus | - |
placenta | very low oxidase and dehydrogenase activities | Homo sapiens | - |
pons | - |
Oryctolagus cuniculus | - |
pons | high rate of dehydrogenase activity | Homo sapiens | - |
skeletal muscle | low oxidase activity | Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
spleen | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + NAD+ + H2O | - |
Homo sapiens | urate + NADH | - |
r | |
xanthine + NAD+ + H2O | - |
Oryctolagus cuniculus | urate + NADH | - |
r |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
-20 | - |
stable up to 10 days | Homo sapiens |
4 | - |
liver extract: conversion of dehydrogenase to oxidase activity, some loss of activity after 7 days, extract from cerebrellum and cerebral cortex: stable for 7 days | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9.2 | trends to increasing activities at higher values | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens | |
NAD+ | - |
Oryctolagus cuniculus | |
NADH | - |
Homo sapiens | |
NADH | - |
Oryctolagus cuniculus |