Inhibitors | Comment | Organism | Structure |
---|---|---|---|
19-hydroxyandrost-4-ene-3,17-dione | competitive with substrates androst-4-ene-3,17-dione and 19-oxoandrost-4-ene-3,17-dione | Homo sapiens | |
19-nortestosterone | competitive inhibitor of both aromatization and cytochrome P450 binding of androst-4-ene-3,17-dione | Homo sapiens | |
19-oxoandrost-4-ene-3,17-dione | competitive with substrates androst-4-ene-3,17-dione and 19-hydroxyandrost-4-ene-3,17-dione | Homo sapiens | |
Aminoglutethimide | 0.005 mM, 54% residual activity | Homo sapiens | |
androst-4-ene-3,17-dione | competitive inhibitor of both aromatization and cytochrome P450 binding of 19-nortestosterone | Homo sapiens | |
diethylaminoethyl-2,2-diphenylvalerate | 0.05 mM, 64% residual activity | Homo sapiens | |
KCN | 5 mM, 80% residual activity | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the rate of entry of the first electron into the oxidized P450 substrate complex may be rate limiting in the aromatization of C19 but not C18 steroids | Homo sapiens | ? | - |
? |