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Literature summary for 1.14.14.137 extracted from

  • Son, S.; Chitnis, V.R.; Liu, A.; Gao, F.; Nguyen, T.N.; Ayele, B.T.
    Abscisic acid metabolic genes of wheat (Triticum aestivum L.) identification and insights into their functionality in seed dormancy and dehydration tolerance (2016), Planta, 244, 429-447 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene TaCYP707A1B, cloning from seedlings, expression analysis, ectopic expression of genes TaNCED2A and TaCYP707A1B in Arabidopsis thaliana Col-0 ecotype, using Agrobacterium tumefaciens AGL1 transformation method, results in altered seed abscisic acid level and dormancy with no effect on leaf abscisic acid content and transpirational water loss, phenotypes, overview. Quantitative and semiquantitative real-time and RT-PCR expression analysis Triticum aestivum

Protein Variants

Protein Variants Comment Organism
additional information generation of Tricticum aestivum mutant lines cyp707a1, cyp707a2, and cyp707a1/cyp707a2, phenotypes, overview Triticum aestivum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(+)-abscisate + [reduced NADPH-hemoprotein reductase] + O2 Triticum aestivum
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8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O
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?

Organism

Organism UniProt Comment Textmining
Triticum aestivum B8QBY2 cv. AC Domain
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Source Tissue

Source Tissue Comment Organism Textmining
seedling spatiotemporal expression pattern of TaCYP707A1B gene in hexaploid wheat Triticum aestivum
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silique CYP707A1 transcripts are highly abundant in the silique Triticum aestivum
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-abscisate + [reduced NADPH-hemoprotein reductase] + O2
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Triticum aestivum 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Synonyms

Synonyms Comment Organism
ABA 8'-hydroxylase
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Triticum aestivum
ABA8'OH
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Triticum aestivum
CYP707A1
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Triticum aestivum
cytochrome P450 monooxygenase 707A1
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Triticum aestivum
TaABA8'OH1
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Triticum aestivum
TaCYP707A1B
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Triticum aestivum

Cofactor

Cofactor Comment Organism Structure
cytochrome P-450
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Triticum aestivum
NADPH-hemoprotein reductase A flavoprotein containing both FMN and FAD. This enzyme catalyses the transfer of electrons from NADPH, an obligatory two-electron donor, to microsomal P-450 monooxygenases, EC 1.14.14._ Triticum aestivum

General Information

General Information Comment Organism
evolution the enzyme is a member of the CYP707A family Triticum aestivum
malfunction deletion in TaABA8'OH1 leads to increased abscisic acid level in the spikes and therefore increased drought sensitivity, phenotype, overview. Germination of the cyp707a1 cyp707a2 seeds appear not to be affected by the cold treatment, which induces early germination phenotype in the control wild-type and TaCYP707A1B-C seeds of transgenic Arabidospis thaliana, similar rate of transpirational water loss between the wild-type and mutant TaNCED2A-OE, cyp707a1/cyp707a2 and TaCYP707A1B-C lines during the entire period of dehydration Triticum aestivum
metabolism biosynthesis and catabolism of abscisic acid (ABA) in plants are primarily regulated by 9-cis-epoxycarotenoid dioxygenases (NCEDs) and ABA 8'-hydroxylase (ABA8'OH), respectively Triticum aestivum
physiological function the abscisic acid catabolic enzyme ABA8'OH is encoded by members of the cytochrome P450 monooxygenase 707A (CYP707A) gene family, which play important roles in regulating seed abscisic acid level during seed development and therefore dormancy. Role of the B genome copy of the cytochrome P450 monooxygenase 707A1 (CYP707A1) gene of hexaploid wheat (TaCYP707A1B), which encodes ABA8'OH, in regulating seed dormancy and leaf dehydration tolerance Triticum aestivum