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Information on EC 1.14.14.137 - (+)-abscisic acid 8'-hydroxylase

for references in articles please use BRENDA:EC1.14.14.137

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IUBMB Comments

A cytochrome P-450 (heme-thiolate) protein found in plants. Catalyses the first step in the oxidative degradation of abscisic acid and is considered to be the pivotal enzyme in controlling the rate of degradation of this plant hormone . CO inhibits the reaction, but its effects can be reversed by the presence of blue light . The 8'-hydroxyabscisate formed can be converted into (-)-phaseic acid, most probably spontaneously.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
  • 1.14.14.137
  • dormancy
  • 9-cis-epoxycarotenoid
  • imbibition
  • phaseic
  • 8'-hydroxylation
  • pre-harvest
  • after-ripening
  • +-abscisic
  • aba-responsive
  • diniconazole
  • epoxycarotenoids
  • agriculture

Synonyms
aba 8'-hydroxylase, cyp707a, cyp707a2, cyp707a3, cyp707a1, abscisic acid 8'-hydroxylase, ahcyp707a1, taaba8'oh1, aba-8'-hydroxylase, ahcyp707a2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+)-abscisate + [reduced NADPH-hemoprotein reductase] + O2 = 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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