Disease on EC 4.6.1.23 - ribotoxin
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Adenocarcinoma
Ultrastructural changes induced by alpha-sarcin in a human pulmonary tumor grown in naked mice.
Aspergillosis
Analysis of the major proteins secreted by the human opportunistic pathogen Aspergillus fumigatus under in vitro conditions.
Aspergillosis
Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections.
Aspergillosis
Use of recombinant mitogillin for improved serodiagnosis of Aspergillus fumigatus-associated diseases.
Aspergillosis, Allergic Bronchopulmonary
Immunodominant peptide epitopes of allergen, Asp f 1 from the fungus Aspergillus fumigatus.
Brain Neoplasms
Purification, characterization and cytotoxicity assessment of Ageritin: The first ribotoxin from the basidiomycete mushroom Agrocybe aegerita.
Breast Neoplasms
Immunoconjugate generation between the ribosome inactivating protein restrictocin and an anti-human breast carcinoma MAB.
Carcinoma
Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein alpha-sarcin from Aspergillus giganteus.
Carcinoma
Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A.
Colorectal Neoplasms
Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin ?-sarcin in nude mice bearing human colorectal cancer xenografts.
Colorectal Neoplasms
Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin ?-Sarcin- or RNase T1-Based Immunotoxins.
Infections
Analysis of the major proteins secreted by the human opportunistic pathogen Aspergillus fumigatus under in vitro conditions.
Infections
Beauveria bassiana ribotoxin inhibits insect immunity responses to facilitate infection via host translational blockage.
Infections
Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes.
Infections
Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis.
Influenza in Birds
Effects of edeine, hygromycin B and alpha-Sarcin on influenza virus reproduction.
Influenza, Human
Effects of edeine, hygromycin B and alpha-Sarcin on influenza virus reproduction.
Invasive Pulmonary Aspergillosis
Aspergillus fumigatus and Its Allergenic Ribotoxin Asp f I: Old Enemies but New Opportunities for Urine-Based Detection of Invasive Pulmonary Aspergillosis Using Lateral-Flow Technology.
Invasive Pulmonary Aspergillosis
Construction and pathogenicity of Aspergillus fumigatus mutants that do not produce the ribotoxin restrictocin.
Invasive Pulmonary Aspergillosis
Effects of alkaline protease or restrictocin deficient mutants of Aspergillus fumigatus on human polymorphonuclear leukocytes.
Invasive Pulmonary Aspergillosis
Use of recombinant mitogillin for improved serodiagnosis of Aspergillus fumigatus-associated diseases.
Mycoses
Characterization of the Aspergillus fumigatus chitosanase CsnB and evaluation of its potential use in serological diagnostics.
Neoplasms
Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.
Neoplasms
Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin ?-sarcin in nude mice bearing human colorectal cancer xenografts.
Neoplasms
Evaluation of mitogillin (NSC-69529) in the treatment of naturally occurring canine neoplasms.
Neoplasms
Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin ?-Sarcin- or RNase T1-Based Immunotoxins.
Neoplasms
Kinetic study of the cytotoxic effect of alpha-sarcin, a ribosome inactivating protein from Aspergillus giganteus, on tumour cell lines: protein biosynthesis inhibition and cell binding.
Neoplasms
Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector.
Neoplasms
Purification, characterization and cytotoxicity assessment of Ageritin: The first ribotoxin from the basidiomycete mushroom Agrocybe aegerita.
Neoplasms
Study of the interaction between the antitumour protein alpha-sarcin and phospholipid vesicles.
Neoplasms
Toxicity and membrane perturbation properties of the ribotoxin-like protein Ageritin.
Neoplasms
Ultrastructural changes induced by alpha-sarcin in a human pulmonary tumor grown in naked mice.
Neuroblastoma
Ageritin from poplar mushrooms: scale-up purification and cytotoxicity towards undifferentiated and differentiated SH-SY5Y cells.
Rhabdomyosarcoma
Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis.
Rotavirus Infections
Rotaviruses induce an early membrane permeabilization of MA104 cells and do not require a low intracellular Ca2+ concentration to initiate their replication cycle.
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