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Disease on EC 3.1.3.11 - fructose-bisphosphatase and Organism(s) Homo sapiens

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
6-phosphofructokinase deficiency
Pyrophosphate-dependent phosphofructo-1-kinase complements fructose 1,6-bisphosphatase but not phosphofructokinase deficiency in Escherichia coli.
Acidosis
Carbohydrate metabolism in rat kidney: heterogeneous distribution of glycolytic and gluconeogenic key enzymes.
Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation.
Fructose-1,6-bisphosphatase deficiency as a cause of recurrent hypoglycemia and metabolic acidosis: Clinical and molecular findings in Malaysian patients.
Fructose-1,6-bisphosphatase deficiency with confirmed molecular diagnosis. An important cause of hypoglycemia in children.
Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency.
Intravenous glycerol therapy should not be used in patients with unrecognized fructose-1,6-bisphosphatase deficiency.
Status epilepticus due to fructose-1,6-bisphosphatase deficiency caused by FBP1 gene mutation.
Acidosis, Lactic
Fructose-1,6-bisphosphatase deficiency with confirmed molecular diagnosis. An important cause of hypoglycemia in children.
Fructose-1,6-Bisphosphatase Deficiency: A Case of a Successful Pregnancy by Closely Monitoring Metabolic Control.
Genetic analysis of fructose-1,6-bisphosphatase (FBPase) deficiency in nine consanguineous Pakistani families.
Infantile lactic acidosis due to hereditary fructose 1,6-diphosphatase deficiency.
Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis.
Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency.
Problems in the congenital lactic acidoses.
Apnea
Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency.
Asthma
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Brain Ischemia
Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia.
Breast Neoplasms
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer.
Fructose-1,6-bisphosphatase is a novel regulator of Wnt/?-Catenin pathway in breast cancer.
Invalidation of mitophagy by FBP1-mediated repression promotes apoptosis in breast cancer.
Carcinogenesis
Fructose?1,6?bisphosphatase?1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Loss of fructose-1,6-bisphosphatase induces glycolysis and promotes apoptosis resistance of cancer stem-like cells: an important role in hexavalent chromium-induced carcinogenesis.
Carcinoma
Fructose 1,6-Bisphosphatase 1 Expression Reduces 18F-FDG Uptake in Clear Cell Renal Cell Carcinoma.
Carcinoma, Embryonal
One of the retinoic acid-inducible cDNA clones in mouse embryonal carcinoma F9 cells encodes a novel isoenzyme of fructose 1,6-bisphosphatase.
Carcinoma, Hepatocellular
A case of minimal deviation hepatoma in man with elevated liver-type pyruvate kinase isozyme.
A selective system for hepatoma cells producing gluconeogenic enzymes.
CCAAT-enhancer binding protein-? (C/EBP?) and hepatocyte nuclear factor 4? (HNF4?) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells.
Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma.
Enzyme deviation patterns in primary rat hepatomas induced by sequential administration of two chemically different carcinogens.
Fructose 1,6-diphosphatase of rat tissues and transplantable rat hepatomas.
Fructose-1,6-Bisphosphatase 1 Reduces (18)F FDG Uptake in Hepatocellular Carcinoma.
Profiles of carbohydrate-metabolizing enzymes in human hepatocellular carcinomas and preneoplastic livers.
Rev-erb? activation down-regulates hepatic Pck1 enzyme to lower plasma glucose in mice.
Carcinoma, Renal Cell
Fructose 1,6-Bisphosphatase 1 Expression Reduces 18F-FDG Uptake in Clear Cell Renal Cell Carcinoma.
Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
Re: Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
Cholangiocarcinoma
Forced overexpression of FBP1 inhibits proliferation and metastasis in cholangiocarcinoma cells via Wnt/?-catenin pathway.
Cholestasis
Evaluation of key gluconeogenic enzymes in experimental biliary obstruction.
Dehydration
Antioxidative defense system, pigment composition, and photosynthetic efficiency in two wheat cultivars subjected to drought
Mild Water Stress of Phaseolus vulgaris Plants Leads to Reduced Starch Synthesis and Extractable Sucrose Phosphate Synthase Activity.
Diabetes Mellitus
Fructose-1,6-bisphosphatase inhibitors: A new valid approach for management of type 2 diabetes mellitus.
Impaired regulation of hepatic fructose-1,6-biphosphatase in the New Zealand Obese mouse: an acquired defect.
In silico identification of structure requirement for novel thiazole and oxazole derivatives as potent fructose 1,6-bisphosphatase inhibitors.
Mononuclear and polymorphonuclear leukocytes show increased fructose-1,6-bisphosphatase activity in patients with type 1 diabetes mellitus.
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Toward the Prediction of FBPase Inhibitory Activity Using Chemoinformatic Methods.
Diabetes Mellitus, Experimental
Hormonal effects on structure and catalytic properties of fructose 1,6-bisphosphatase.
[Level of fructose-2,6-bisphosphate and activity of fructose-1,6-bisphosphatase in hepatocyte suspensions in streptozotocin diabetes]
Diabetes Mellitus, Type 1
Mononuclear and polymorphonuclear leukocytes show increased fructose-1,6-bisphosphatase activity in patients with type 1 diabetes mellitus.
Diabetes Mellitus, Type 2
Contributions of Hepatic Gluconeogenesis Suppression and Compensative Glycogenolysis on the Glucose-Lowering Effect of CS-917, a Fructose 1,6-Bisphosphatase Inhibitor, in Non-obese Type 2 Diabetes Goto-Kakizaki Rats.
Determination of protein-ligand binding constants of a cooperatively regulated tetrameric enzyme using electrospray mass spectrometry.
Development of disulfide-derived fructose-1,6-bisphosphatase (FBPase) covalent inhibitors for the treatment of type 2 diabetes.
Discovery of fructose-1,6-bisphosphatase inhibitors for the treatment of type 2 diabetes.
Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes.
Enzymes involved in l-lactate metabolism in humans.
Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis.
Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes.
Fructose-1,6-bisphosphatase inhibitors: A new valid approach for management of type 2 diabetes mellitus.
Fructose-1,6-bisphosphatase: genetic and physical mapping to human chromosome 9q22.3 and evaluation in non-insulin-dependent diabetes mellitus.
Identification of activating enzymes of a novel FBPase inhibitor prodrug, CS-917.
Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction.
Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand obese mouse model of NIDDM.
In silico identification of structure requirement for novel thiazole and oxazole derivatives as potent fructose 1,6-bisphosphatase inhibitors.
Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes.
MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.
Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase.
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Toward the Prediction of FBPase Inhibitory Activity Using Chemoinformatic Methods.
Use of Graph Based Descriptors for Determination of Structural Features Causing Modulation of Fructose-1,6-Bisphosphatase.
fructokinase deficiency
Inborn Errors of Fructose Metabolism. What Can We Learn from Them?
Fructose Intolerance
Inborn Errors of Fructose Metabolism. What Can We Learn from Them?
fructose-2,6-bisphosphate 2-phosphatase deficiency
Diagnosis of fructose-1,6-bisphosphatase deficiency using cultured lymphocyte fraction: a secure and noninvasive alternative to liver biopsy.
Fructose-1,6-bisphosphatase deficiency with confirmed molecular diagnosis. An important cause of hypoglycemia in children.
Two newly identified genomic mutations in a Japanese female patient with fructose-1,6-bisphosphatase (FBPase) deficiency.
fructose-bisphosphatase deficiency
A Chinese Adult Patient with Fructose 1,6-bisphosphatase Deficiency.
A Japanese boy with fructose-1,6-bisphosphatase deficiency who had a novel
A potential role for muscle in glucose homeostasis: in vivo kinetic studies in glycogen storage disease type 1a and fructose-1,6-bisphosphatase deficiency.
A summary of molecular genetic findings in fructose-1,6-bisphosphatase deficiency with a focus on a common long-range deletion and the role of MLPA analysis.
cDNA sequences encoding human fructose 1,6-bisphosphatase from monocytes, liver and kidney: application of monocytes to molecular analysis of human fructose 1,6-bisphosphatase deficiency.
Clinical and Molecular Characterization of Patients with Fructose 1,6-Bisphosphatase Deficiency.
Detection of heterozygotes for fructose 1,6-diphosphatase deficiency by measuring fructose 1,6-diphosphatase activity in their cultured peripheral lymphocytes.
Diagnosis of fructose-1,6-bisphosphatase deficiency using cultured lymphocyte fraction: a secure and noninvasive alternative to liver biopsy.
Diagnosis of fructose-1,6-bisphosphatase deficiency using leukocytes: normal leukocyte enzyme activity in three female patients.
Diagnosis of inborn errors of metabolism using filter paper urine, urease treatment, isotope dilution and gas chromatography-mass spectrometry.
Effect of phosphoglycerate mutase and fructose 1,6-bisphosphatase deficiency on symbiotic Burkholderia phymatum.
Exon 2 deletion represents a common mutation in Turkish patients with fructose-1,6-bisphosphatase deficiency.
False positive fructose loading: a pitfall in the diagnosis of fructose-1,6-bisphosphatase deficiency.
Fructose 1,6-bisphosphatase deficiency as a cause of childhood interstitial lung disease.
Fructose 1,6-bisphosphatase deficiency: clinical, biochemical and genetic features in French patients.
Fructose 1,6-bisphosphatase deficiency: enzyme and mutation analysis performed on calcitriol-stimulated monocytes with a note on long-term prognosis.
Fructose-1,6-bisphosphatase deficiency as a cause of recurrent hypoglycemia and metabolic acidosis: Clinical and molecular findings in Malaysian patients.
Fructose-1,6-bisphosphatase deficiency caused by a novel homozygous Alu element insertion in the FBP1 gene and delayed diagnosis.
Fructose-1,6-bisphosphatase deficiency presented with complex febrile convulsion.
Fructose-1,6-bisphosphatase deficiency with confirmed molecular diagnosis. An important cause of hypoglycemia in children.
Fructose-1,6-Bisphosphatase Deficiency: A Case of a Successful Pregnancy by Closely Monitoring Metabolic Control.
Fructose-1,6-bisphosphatase deficiency: severe phenotype with normal leukocyte enzyme activity.
Genetic analysis of patients with fructose-1,6-bisphosphatase deficiency.
Genetic Analysis of Tyrosinemia Type 1 and Fructose-1, 6 Bisphosphatase Deficiency Affected Pakistani Cohorts.
Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency.
Identification of a genetic mutation in a family with fructose-1,6- bisphosphatase deficiency.
Identification of genetic mutations in Japanese patients with fructose-1,6-bisphosphatase deficiency.
Impaired ketogenesis in fructose-1,6-bisphosphatase deficiency: a pitfall in the investigation of hypoglycaemia.
Inborn Errors of Fructose Metabolism. What Can We Learn from Them?
Infantile lactic acidosis due to hereditary fructose 1,6-diphosphatase deficiency.
Inherited metabolic disorders in Thailand.
Intravenous glycerol therapy should not be used in patients with unrecognized fructose-1,6-bisphosphatase deficiency.
Lactic acidosis in childhood.
Metabolic and biochemical studies in fructose 1,6-diphosphatase deficiency.
Muscle fructose 1,6-diphosphatase deficiency associated with an atypical central core disease.
Mutation spectrum in patients with fructose-1,6-bisphosphatase deficiency.
Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency.
Novel Mutation with Fructose-1,6-Bisphosphatase Deficiency.
Novel mutations in patients with fructose-1,6-bisphosphatase deficiency.
Pitfall in the Diagnosis of Fructose-1,6-Bisphosphatase Deficiency: Difficulty in Detecting Glycerol-3-Phosphate with Solvent Extraction in Urinary GC/MS Analysis.
Status epilepticus due to fructose-1,6-bisphosphatase deficiency caused by FBP1 gene mutation.
The fructose-1,6-bisphosphatase deficiency and the p.(Lys204ArgfsTer72) variant.
Three successful pregnancies through dietary management of fructose-1,6-bisphosphatase deficiency.
Transient pseudo-hypertriglyceridemia: a useful biochemical marker of fructose-1,6-bisphosphatase deficiency.
[Congenital fructose 1,6 diphosphatase deficiency. Description of a case]
[Fructose 1,6-bisphosphatase deficiency as a cause of recessive serious hypoglycaemia]
[Fructose 1,6-diphosphatase deficiency in 2 sisters]
[Fructose-1,6-bisphosphatase deficiency]
Glycogen Storage Disease
A potential role for muscle in glucose homeostasis: in vivo kinetic studies in glycogen storage disease type 1a and fructose-1,6-bisphosphatase deficiency.
Lactic acidosis in childhood.
Hepatitis
Fructose 1,6-bisphosphatase in the diagnosis of chronic hepatitis. II. Classification of chronic hepatitis based on fructose 1,6-bisphosphatase and other laboratory data.
Science letters: Proteomic analysis of differentially expressed proteins in mice with concanavalin A-induced hepatitis.
Hepatitis, Chronic
Fructose 1,6-bisphosphatase in the diagnosis of chronic hepatitis. I. Activity measurements of fructose 1,6-bisphosphatase in human serum.
Fructose 1,6-bisphosphatase in the diagnosis of chronic hepatitis. II. Classification of chronic hepatitis based on fructose 1,6-bisphosphatase and other laboratory data.
Profiles of carbohydrate-metabolizing enzymes in human hepatocellular carcinomas and preneoplastic livers.
Hepatomegaly
Problems in the congenital lactic acidoses.
Homocystinuria
Inherited metabolic disorders in Thailand.
Hyperglycemia
CS-917, a fructose 1,6-bisphosphatase inhibitor, improves postprandial hyperglycemia after meal loading in non-obese type 2 diabetic Goto-Kakizaki rats.
Developmental aspects of transcription of fructose-1,6-bisphosphatase in newborn dogs.
Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes.
Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in zucker diabetic Fatty rats.
Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.
SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.
Hyperglycinemia, Nonketotic
Inherited metabolic disorders in Thailand.
Hyperinsulinism
Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison with troglitazone.
Developmental aspects of transcription of fructose-1,6-bisphosphatase in newborn dogs.
Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.
Hyperthyroidism
The rate of substrate cycling between fructose 6-phosphate and fructose 1,6-bisphosphate in skeletal muscle from cold-exposed, hyperthyroid or acutely exercised rats.
Hyperventilation
Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency.
Hypoglycemia
A central role of RLIP76 in regulation of glycemic control.
Fructose-1,6-bisphosphatase deficiency as a cause of recurrent hypoglycemia and metabolic acidosis: Clinical and molecular findings in Malaysian patients.
Fructose-1,6-bisphosphatase deficiency with confirmed molecular diagnosis. An important cause of hypoglycemia in children.
Fructose-1,6-Bisphosphatase Deficiency: A Case of a Successful Pregnancy by Closely Monitoring Metabolic Control.
Genetic analysis of fructose-1,6-bisphosphatase (FBPase) deficiency in nine consanguineous Pakistani families.
Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency.
Intravenous glycerol therapy should not be used in patients with unrecognized fructose-1,6-bisphosphatase deficiency.
Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis.
Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency.
Novel Fructose-1,6-bisphosphatase Gene Mutation in Two Siblings.
Status epilepticus due to fructose-1,6-bisphosphatase deficiency caused by FBP1 gene mutation.
Insulin Resistance
Developmental aspects of transcription of fructose-1,6-bisphosphatase in newborn dogs.
Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver.
Mitigating Perspectives of Asiatic acid in the Renal derangements of Streptozotocin-Nicotinamide induced Diabetic Rats.
Ketosis
Genetic analysis of fructose-1,6-bisphosphatase (FBPase) deficiency in nine consanguineous Pakistani families.
Status epilepticus due to fructose-1,6-bisphosphatase deficiency caused by FBP1 gene mutation.
Leigh Disease
Lactic acidosis in childhood.
Leukemia
Induction and turnover of fructose 1,6-bisphosphatase in HL-60 leukemia cells by calcitriol.
Induction of fructose 1,6-bisphosphatase in HL-60 leukemia cells by retinoic acid.
Lissencephaly
Armadillo Repeat Containing 8alpha Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins.
Liver Cirrhosis
Profiles of carbohydrate-metabolizing enzymes in human hepatocellular carcinomas and preneoplastic livers.
Liver Diseases
Proteomic signature of acute liver failure: from discovery and verification in a pig model to confirmation in humans.
Liver Neoplasms
LIX1-like protein promotes liver cancer progression via miR-21-3p-mediated inhibition of fructose-1,6-bisphosphatase.
Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.
Lung Diseases, Interstitial
Fructose 1,6-bisphosphatase deficiency as a cause of childhood interstitial lung disease.
Lymphoma
Mouse thymoma cell line expresses a gluconeogenic enzyme, fructose 1,6-bisphosphatase.
Magnesium Deficiency
Hepatic gluconeogenic enzymes, plasma insulin and glucagon response to magnesium deficiency and fasting.
Menkes Kinky Hair Syndrome
Inherited metabolic disorders in Thailand.
Mucopolysaccharidoses
Inherited metabolic disorders in Thailand.
Myopathy, Central Core
Muscle fructose 1,6-diphosphatase deficiency associated with an atypical central core disease.
Nasopharyngeal Carcinoma
FBP1 enhances the radiosensitivity by suppressing glycolysis via the FBXW7/mTOR axis in nasopharyngeal carcinoma cells.
Neoplasms
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer.
Abnormal muscle fructose bisphosphatase activity in malnourished cancer patients.
Biochemical alterations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors from rats subjected to caloric restriction.
Breast Cancer Subtypes Underlying EMT-Mediated Catabolic Metabolism.
Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer.
Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma.
Dual targeting of histone methyltransferase G9a and DNA-methyltransferase 1 for the treatment of experimental hepatocellular carcinoma.
E3 ubiquitin ligase UBR5 promotes pancreatic cancer growth and aerobic glycolysis by downregulating FBP1 via destabilization of C/EBP?.
Effect of tumor necrosis factor on enzymes of gluconeogenesis in the rat.
Enzyme deviation patterns in primary rat hepatomas induced by sequential administration of two chemically different carcinogens.
Epigenetic Marks Repressing Gluconeogenesis in Liver and Kidney Cancer.
FBP1 enhances the radiosensitivity by suppressing glycolysis via the FBXW7/mTOR axis in nasopharyngeal carcinoma cells.
FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome.
FBP1 regulates proliferation, metastasis, and chemoresistance by participating in C-MYC/STAT3 signaling axis in ovarian cancer.
Fructose 1,6-Bisphosphatase 1 Expression Reduces 18F-FDG Uptake in Clear Cell Renal Cell Carcinoma.
Fructose-1,6-Bisphosphatase 1 Reduces (18)F FDG Uptake in Hepatocellular Carcinoma.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction.
Fructose-1,6-bisphosphatase is a novel regulator of Wnt/?-Catenin pathway in breast cancer.
Fructose-1,6-bisphosphatase loss modulates STAT3-dependent expression of PD-L1 and cancer immunity.
Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
Fructose?1,6?bisphosphatase?1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Gluconeogenesis in cancer cells - Repurposing of a starvation-induced metabolic pathway?
Gluconeogenesis in Cancer: Function and Regulation of PEPCK, FBPase, and G6Pase.
HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.
Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction.
Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression.
Invalidation of mitophagy by FBP1-mediated repression promotes apoptosis in breast cancer.
Knockdown of FBP1 enhances radiosensitivity in prostate cancer cells by activating autophagy.
Loss of fructose-1,6-bisphosphatase induces glycolysis and promotes apoptosis resistance of cancer stem-like cells: an important role in hexavalent chromium-induced carcinogenesis.
Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients.
Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.
Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.
Phenolic glycosides and other constituents from the bark of Magnolia officinalis.
Prenatal alcohol exposure alters phosphorylation and glycosylation of proteins in rat offspring liver.
Profiles of carbohydrate-metabolizing enzymes in human hepatocellular carcinomas and preneoplastic livers.
Restoration of FBP1 suppressed Snail-induced epithelial to mesenchymal transition in hepatocellular carcinoma.
The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumors.
The Glycogen Shunt Maintains Glycolytic Homeostasis and the Warburg Effect in Cancer.
The Reverse Warburg Effect is Associated with Fbp2-Dependent Hif1? Regulation in Cancer Cells Stimulated by Fibroblasts.
Nephrotic Syndrome
Urinary fructose-1,6-bisphosphatase activity as a marker of the damage to the renal proximal tubules in children with idiopathic nephrotic syndrome.
Obesity
Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver.
The liver: Key in regulating appetite and body weight.
The role of liver fructose-1,6-bisphosphatase in regulating appetite and adiposity.
Obesity, Morbid
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Pancreatic Neoplasms
Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction.
Periodontitis
Acid-base status and fructose diphosphatase activity in rats exposed to fluoride and induced periodontitis.
Phenylketonurias
Inherited metabolic disorders in Thailand.
Propionic Acidemia
Inherited metabolic disorders in Thailand.
Lactic acidosis in childhood.
Proteinuria
Urinary fructose-1,6-bisphosphatase activity as a marker of the damage to the renal proximal tubules in children with idiopathic nephrotic syndrome.
Pyelonephritis
[Assessment of fructose-1,6-biphosphatase in urine of children with acute pyelonephritis]
Sarcoma
Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis.
High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.
Seizures
Status epilepticus due to fructose-1,6-bisphosphatase deficiency caused by FBP1 gene mutation.
Seizures, Febrile
Fructose-1,6-bisphosphatase deficiency presented with complex febrile convulsion.
Starvation
A selective autophagy pathway that degrades gluconeogenic enzymes during catabolite inactivation.
Carbohydrate metabolism in rat kidney: heterogeneous distribution of glycolytic and gluconeogenic key enzymes.
Comparison between starvation and consumption of a high protein diet: plasma insulin and glucagon and hepatic activities of gluconeogenic enzymes during the first 24 hours.
Cyclophilin A mediates Vid22p function in the import of fructose-1,6-bisphosphatase into Vid vesicles.
Degradation of the Gluconeogenic Enzyme Fructose-1, 6-Bisphosphatase is Dependent on the Vacuolar ATPase.
Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation.
Effect of starvation on fructose diphosphatase, glucose-6-phosphatase and phosphoglucomutase activities in organs of Pseudemys (Chrysemys) scripta elegans.
Fuel utilization in colonocytes of the rat.
Metabolic adaptation of the renal carbohydrate metabolism. I. Effects of starvation on the gluconeogenic and glycolytic fluxes in the proximal and distal renal tubules.
Predominant periportal expression of the fructose 1,6-bisphosphatase gene in rat liver: dynamics during the daily feeding rhythm and starvation-refeeding cycle.
Stress-induced lncRNAs evade nuclear degradation and enter the translational machinery.
The key gluconeogenic enzyme fructose-1,6-bisphosphatase is secreted during prolonged glucose starvation and is internalized following glucose re-feeding via the non-classical secretory and internalizing pathways in Saccharomyces cerevisiae.
Status Epilepticus
Status epilepticus due to fructose-1,6-bisphosphatase deficiency caused by FBP1 gene mutation.
Stroke
Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia.
succinate-semialdehyde dehydrogenase [nad(p)+] deficiency
Diagnosis of inborn errors of metabolism using filter paper urine, urease treatment, isotope dilution and gas chromatography-mass spectrometry.
Teratocarcinoma
Various fructose-1,6-bisphosphatase mRNAs in mouse brain, liver, kidney and heart.
Thymoma
Mouse thymoma cell line expresses a gluconeogenic enzyme, fructose 1,6-bisphosphatase.
Tuberculosis
Crystallization and preliminary X-ray characterization of the glpX-encoded class II fructose-1,6-bisphosphatase from Mycobacterium tuberculosis.
glpX Gene of Mycobacterium tuberculosis: Heterologous Expression, Purification, and Enzymatic Characterization of the Encoded Fructose 1,6-bisphosphatase II.
Mutagenesis of threonine to serine in the active site of Mycobacterium tuberculosis fructose-1,6-bisphosphatase (Class II) retains partial enzyme activity.
Rv2131c gene product: an unconventional enzyme that is both inositol monophosphatase and fructose-1,6-bisphosphatase.
Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition.
The Mycobacterium tuberculosis Rv1099c gene encodes a GlpX-like class II fructose 1,6-bisphosphatase.
Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.
Tuberous Sclerosis
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Tyrosinemias
Genetic Analysis of Tyrosinemia Type 1 and Fructose-1, 6 Bisphosphatase Deficiency Affected Pakistani Cohorts.
Uterine Cervical Neoplasms
Fructose-1,6-bisphosphatase 2 represses cervical cancer progression via inhibiting aerobic glycolysis through promoting pyruvate kinase isozyme type M2 ubiquitination.
Virus Diseases
Viral infection enables phloem loading of GFP and long-distance trafficking of the protein.
Vitamin A Deficiency
Vitamin A regulates genes involved in hepatic gluconeogenesis in mice: phosphoenolpyruvate carboxykinase, fructose-1,6-bisphosphatase and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.