Disease on EC 2.7.1.68 - 1-phosphatidylinositol-4-phosphate 5-kinase and Organism(s) Homo sapiens
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Anaphylaxis
Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}.
Anemia, Sickle Cell
Characterization of phosphoinositide kinases in normal and sickle anaemia red cells.
Arthritis
Neglected Two-Week-Old Unstable Fracture-Dislocation of the Hip in a 60 Years Old, Managed with Hip Preservation Surgery.
Arthritis
[Early primary total hip arthroplasty for acetabular fractures in elderly patients]
Breast Neoplasms
Amplification of Chromosome 1q Genes Encoding the Phosphoinositide Signalling Enzymes PI4KB, AKT3, PIP5K1A and PI3KC2B in Breast Cancer.
Breast Neoplasms
Coordinated increase in activities of the signal transduction enzymes PI kinase and PIP kinase in human cancer cells.
Breast Neoplasms
Increased signal transduction activity and down-regulation in human cancer cells.
Breast Neoplasms
NEDD4-induced degradative ubiquitination of phosphatidylinositol 4-phosphate 5-kinase ? and its implication in breast cancer cell proliferation.
Breast Neoplasms
Phosphatidylinositol 4,5-bisphosphate and PIP5-kinase Ialpha are required for invadopodia formation in human breast cancer cells.
Breast Neoplasms
Quercetin down-regulates signal transduction in human breast carcinoma cells.
Breast Neoplasms
Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.
Carcinoma
Coordinated increase in activities of the signal transduction enzymes PI kinase and PIP kinase in human cancer cells.
Carcinoma
Decrease in Multidrug Resistance-associated Protein 2 Activities by Knockdown of Phosphatidylinositol 4-phosphate 5-kinase in Hepatocytes and Cancer Cells.
Carcinoma
Synergistic action of tiazofurin and genistein on growth inhibition and differentiation of K-562 human leukemic cells.
Carcinoma, Hepatocellular
1-Phosphatidylinositol 4-phosphate 5-kinase (EC 2.7.1.68): a proliferation- and malignancy-linked signal transduction enzyme.
Carcinoma, Hepatocellular
Decrease in Multidrug Resistance-associated Protein 2 Activities by Knockdown of Phosphatidylinositol 4-phosphate 5-kinase in Hepatocytes and Cancer Cells.
Carcinoma, Hepatocellular
Increased signal transduction activity and down-regulation in human cancer cells.
Carcinoma, Hepatocellular
Intracellular signalling: phosphatidylinositol lipid metabolism in cancer cells.
Carcinoma, Non-Small-Cell Lung
Exosomal circ_PIP5K1A regulates the progression of non-small cell lung cancer and cisplatin sensitivity by miR-101/ABCC1 axis.
Carcinoma, Ovarian Epithelial
Increased signal transduction activity and down-regulation in human cancer cells.
Colonic Neoplasms
Circular RNA PIP5K1A promotes colon cancer development through inhibiting miR-1273a.
Coxa Valga
Femoral Varus Osteotomy for Hip Instability after Traumatic Fracture Dislocations of the Hip Associated with Femoral Head Fractures: A Report of Two Cases.
Dehydration
A gene encoding phosphatidylinositol-4-phosphate 5-kinase is induced by water stress and abscisic acid in Arabidopsis thaliana.
Endometriosis
Circular RNA PIP5K1A (circPIP5K1A) accelerates endometriosis progression by regulating the miR-153-3p/Thymosin Beta-4 X-Linked (TMSB4X) pathway.
Fracture Dislocation
Femoral Varus Osteotomy for Hip Instability after Traumatic Fracture Dislocations of the Hip Associated with Femoral Head Fractures: A Report of Two Cases.
Fracture Dislocation
Ganz Surgical Dislocation of the Hip Is a Safe Technique for Operative Treatment of Pipkin Fractures. Results of a Prospective Trial.
Fracture Dislocation
Posterior wall acetabulum fracture-dislocation with subsequent ipsilateral pipkin IV fracture-dislocation: How many hits can a hip take?
Fracture Dislocation
Surgical dislocation or the modified Heuter anterior approach for Pipkin I and II femoral head fracture dislocations.
Genetic Diseases, Inborn
Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5K?.
Glioma
CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p.
Glioma
Differences in the metabolism of inositol and phosphoinositides by cultured cells of neuronal and glial origin.
Guillain-Barre Syndrome
Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome.
Hip Dislocation
A case of pathological fracture caused by vitamin D insufficiency in a young athlete and a review of the literature.
Hip Dislocation
A treatment strategy to avoid iatrogenic Pipkin type III femoral head fracture-dislocations.
Hip Dislocation
Bilateral irreducible asymmetrical fracture-dislocation of the hip: A case report and literature review.
Hip Dislocation
Bilateral posterior hip dislocation associated with right Pipkin II fracture: A case report.
Hip Dislocation
Failed reduction of posterior hip dislocation accompanied by femoral head fracture: causes and resolving strategy.
Hip Dislocation
Operative versus nonoperative management of Pipkin type-II fractures associated with posterior hip dislocation.
Hip Dislocation
Rotational osteoplasty and bioabsorbable polylactate pin fixation in Pipkin type 2 fracture with acute osteochondral defect: a case report.
Hip Dislocation
Surgical hip dislocation vs arthroscopy for fixation of subfoveal femoral head fractures: A new technique for Pipkin type 1 fractures.
Hip Dislocation
Transfer of osteochondral shell autografts to salvage femoral head impaction injuries in hip trauma patients.
Hip Dislocation
Treatment of Pipkin type I fracture using safe surgical hip dislocation: A case report.
Hip Dislocation
Trochanteric Flip (Ganz) Anterior Hip Dislocation for Fixation of Pipkin Fracture-Dislocations.
Infertility
Role of phosphatidylinositol-4-phosphate 5' kinase (ppk-1) in ovulation of Caenorhabditis elegans.
Influenza, Human
A Ca(2+)-dependent signalling circuit regulates influenza A virus internalization and infection.
Intestinal Diseases
Eimeria maxima phosphatidylinositol 4-phosphate 5-kinase: locus sequencing, characterization, and cross-phylum comparison.
Lung Neoplasms
Exosomal circ_PIP5K1A regulates the progression of non-small cell lung cancer and cisplatin sensitivity by miR-101/ABCC1 axis.
Malaria
A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.
Muscle Weakness
Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca(2+) homeostasis.
Neoplasm Metastasis
Cdk5-mediated phosphorylation regulates phosphatidylinositol 4-phosphate 5-kinase type I ? 90 activity and cell invasion.
Neoplasm Metastasis
Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.
Neoplasms
1-Phosphatidylinositol 4-phosphate 5-kinase (EC 2.7.1.68): a proliferation- and malignancy-linked signal transduction enzyme.
Neoplasms
A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase.
Neoplasms
Coordinated increase in activities of the signal transduction enzymes PI kinase and PIP kinase in human cancer cells.
Neoplasms
Decrease in Multidrug Resistance-associated Protein 2 Activities by Knockdown of Phosphatidylinositol 4-phosphate 5-kinase in Hepatocytes and Cancer Cells.
Neoplasms
Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.
Neoplasms
Overexpression of the amplified Pip4k2beta gene from 17q11-12 in breast cancer cells confers proliferation advantage.
Neoplasms
Phosphatidylinositol phosphate 5-kinase I?i2 in association with Src controls anchorage-independent growth of tumor cells.
Neoplasms
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Neoplasms
Type I Gamma Phosphatidylinositol Phosphate 5-kinase i5 Controls the Ubiquitination and Degradation of a Tumor Suppressor Mitogen-Inducible Gene 6.
Neoplasms
Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.
Neuroblastoma
Differences in the metabolism of inositol and phosphoinositides by cultured cells of neuronal and glial origin.
Neuroblastoma
Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling.
Oculocerebrorenal Syndrome
The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.
Osteoarthritis
Dislocated intra-articular femoral head fracture associated with fracture-dislocation of the hip and acetabulum: report of 12 cases and technical notes on surgical intervention.
Osteonecrosis
Ganz Surgical Dislocation of the Hip Is a Safe Technique for Operative Treatment of Pipkin Fractures. Results of a Prospective Trial.
Osteonecrosis
Pipkin type IV femoral head fractures: a case series and review of literature.
Pancreatic Neoplasms
Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.
Polycystic Kidney Diseases
Apical PtdIns(4,5)P2 is required for ciliogenesis and suppression of polycystic kidney disease.
Prostatic Neoplasms
Profiling and relative quantitation of phosphoinositides by multiple precursor ion scanning based on phosphate methylation and isotopic labeling.
Sarcoma, Avian
Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells.
Stomach Neoplasms
Type Igamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin.
Tuberculosis
Polyphosphate deficiency in Mycobacterium tuberculosis is associated with enhanced drug susceptibility and impaired growth in guinea pigs.
Whooping Cough
Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells.
Wiskott-Aldrich Syndrome
Effect of ovarian hormones on genes promoting dendritic spines in laser-captured serotonin neurons from macaques.