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BRENDA support

Information on EC 2.1.1.235 - dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

for references in articles please use BRENDA:EC2.1.1.235

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IUBMB Comments

The enzyme is involved in the biosynthesis of mycaminose, an essential structural component of the macrolide antibiotic tylosin, which is produced by the bacterium Streptomyces fradiae.

The enzyme appears in viruses and cellular organisms

Synonyms
tylm1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
dTDP-alpha-D-mycaminose biosynthesis
Highest Expressing Human Cell Lines
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