Ligand dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose

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Basic Ligand Information

Molecular Structure
Picture of dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H27N3O14P2
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose
KVYJLJOGNUNRJK-HALQBZCBSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose
show the reaction diagram
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dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose
show the reaction diagram
-
2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose
show the reaction diagram
-
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate = dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
show the reaction diagram
-
-

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (7 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.07
-
pH 7.5, 24°C, cosubstrate: 3.0 mM S-adenosyl-L-methionine

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2766
-
pH 7.5, 24°C, cosubstrate: 3.0 mM S-adenosyl-L-methionine

References & Links

Links to other databases for dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose

ChEBI
PubChem
ChEBI
PubChem