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Information on EC 1.21.3.6 - aureusidin synthase

for references in articles please use BRENDA:EC1.21.3.6

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IUBMB Comments

A copper-containing glycoprotein that plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon). The enzyme is a homologue of plant polyphenol oxidase and catalyses two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2′,-dehydrogenation). H2O2 activates reaction (1) but inhibits reaction (2). Originally considered to act on the phenol but now thought to act mainly on the 4′-O-β-D-glucoside in vivo .

The enzyme appears in viruses and cellular organisms

Synonyms
aureusidin synthase, amas1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 1/2 O2 = aureusidin 6-O-beta-D-glucoside + H2O
show the reaction diagram
2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + O2 = bracteatin 6-O-beta-D-glucoside + H2O
show the reaction diagram
(3)
-
-
-
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + O2 = aureusidin 6-O-beta-D-glucoside + H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
aurone biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links