show all | hide all No of entries

Information on EC 1.14.14.26 - 24-hydroxycholesterol 7alpha-hydroxylase

for references in articles please use BRENDA:EC1.14.14.26
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
A P-450 heme-thiolate protein that is found in liver microsomes and in ciliary non-pigmented epithelium . The enzyme is specific for (24S)-cholest-5-ene-3beta,24-diol, which is formed mostly in the brain by EC 1.14.14.25, cholesterol 24-hydroxylase. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH---hemoprotein reductase.
Specify your search results
Select one or more organisms in this record:
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
cyp39a1, cyp39a1 oxysterol 7alpha-hydroxylase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(24S)-cholest-5-ene-3beta,24-diol + [reduced NADPH-hemoprotein reductase] + O2 = (24S)-cholest-5-ene-3beta,7alpha,24-triol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.