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BRENDA support

Information on EC 1.14.13.218 - 5-methylphenazine-1-carboxylate 1-monooxygenase

for references in articles please use BRENDA:EC1.14.13.218

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IUBMB Comments

The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. It can also act on phenazine-1-carboxylate, converting it into phenazin-1-ol.

The enzyme appears in viruses and cellular organisms

Synonyms
PA4217, phzS, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-methylphenazine-1-carboxylate + NADH + O2 = pyocyanin + NAD+ + CO2 + H2O
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
pyocyanin biosynthesis
Highest Expressing Human Cell Lines
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