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Information on EC 1.1.99.32 - L-sorbose 1-dehydrogenase

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IUBMB Comments
The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors.
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The expected taxonomic range for this enzyme is: Alphaproteobacteria
Synonyms
L-sorbose dehydrogenase, PQQ-dependent L-sorbose dehydrogenase, SDH, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor
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