Disease on EC 1.1.3.8 - L-gulonolactone oxidase
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Ascorbic Acid Deficiency
Intragenic deletion in the gene encoding L-gulonolactone oxidase causes vitamin C deficiency in pigs.
Ascorbic Acid Deficiency
Requirement for ascorbic acid in a rat mutant unable to synthesize ascorbic acid.
Ascorbic Acid Deficiency
Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency.
Ascorbic Acid Deficiency
The L-gulono-gamma-lactone oxidase gene (GULO) which is a candidate for vitamin C deficiency in pigs maps to chromosome 14.
Ascorbic Acid Deficiency
Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice.
Carcinoma, Hepatocellular
Gulonolactone Addition to Human Hepatocellular Carcinoma Cells with Gene Transfer of Gulonolactone Oxidase Restores Ascorbate Biosynthesis and Reduces Hypoxia Inducible Factor 1.
Carcinoma, Hepatocellular
Vitamin C deficiency aggravates tumor necrosis factor ?-induced insulin resistance.
Chronic Limb-Threatening Ischemia
Clinical and anatomical variables associated in the literature to limb graft occlusion after endovascular aneurysm repair compared to the experience of a tertiary referral center.
Deficiency Diseases
Intravascularly administered crosslinked immunoprecipitates of gulonolactone oxidase are toxic and rapidly cleared from the circulation.
Fractures, Spontaneous
Genome wide analysis of sex difference in gene expression profiles of bone formations using sfx mice and BXD RI strains.
Fractures, Spontaneous
Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells.
Fractures, Spontaneous
Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency.
Infections
In situ SEM, TEM and AFM studies of the antimicrobial activity of lemon grass oil in liquid and vapour phase against Candida albicans.
Infections
Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice.
Infections
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation.
Influenza, Human
Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice.
Insulin Resistance
Vitamin C deficiency aggravates tumor necrosis factor ?-induced insulin resistance.
l-gulonolactone oxidase deficiency
A missense mutation of L-gulono-gamma-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid.
l-gulonolactone oxidase deficiency
Expression of the mutant gene for L-gulono-gamma-lactone oxidase in scurvy-prone rats.
l-gulonolactone oxidase deficiency
L-gulono-gamma-lactone oxidase deficiency in rats with osteogenic disorder: enzymological and immunochemical studies.
Neoplasms
Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas.
Neoplasms
Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice.
Pancreatic Diseases
'Do research with seriousness and perseverance'. An interview with Prof. Lucio Gullo. Interview by Martin E. Fernandez-Zapico.
Riboflavin Deficiency
L-gulonolactone oxidase activity and vitamin C status in riboflavin-deficient rats.
Scurvy
A missense mutation of L-gulono-gamma-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid.
Scurvy
Body pool and synthesis of ascorbic acid in adult sea lamprey (Petromyzon marinus): An agnathan fish with gulonolactone oxidase activity
Scurvy
Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C.
Scurvy
Feasibility of using an isolated intestinal segment as an artificial organ for enzyme replacement therapy.
Scurvy
Immunologic evidence that the gene for L-gulono-gamma-lactone oxidase is not expressed in animals subject to scurvy.
Scurvy
Intravascularly administered crosslinked immunoprecipitates of gulonolactone oxidase are toxic and rapidly cleared from the circulation.
Seizures
Genetic features of oligodendrogliomas and presence of seizures. The relationship of seizures and genetics in LGOs.
Tuberculosis
Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase.
Vitamin E Deficiency
Formation of malonaldehyde in vitamin E deficiency and its relation to the inhibition of gulonolactone oxidase.
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