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The enzyme appears in viruses and cellular organisms
Synonyms 2-hydroxy fatty acid oxidase, dehydrogenase, L-2-hydroxy fatty acid, L-2-hydroxy fatty acid dehydrogenase, more
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2-hydroxy fatty acid oxidase
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dehydrogenase, L-2-hydroxy fatty acid
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L-2-hydroxy fatty acid dehydrogenase
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(S)-2-hydroxystearate + NAD+ = 2-oxostearate + NADH + H+
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(S)-2-hydroxystearate:NAD+ oxidoreductase
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L-2-hydroxy fatty acid + NAD+
2-keto fatty acid + NADH + H+
L-2-hydroxystearate + NAD+
2-oxostearate + NADH
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Substrates: - Products: -
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L-2-hydroxystearate + NAD+
2-oxostearate + NADH + H+
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L-2-hydroxy fatty acid + NAD+
2-keto fatty acid + NADH + H+
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L-2-hydroxy fatty acid + NAD+
2-keto fatty acid + NADH + H+
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Substrates: intermediate product in the alpha-oxidation of normal and/or branched long-chain fatty acids Products: -
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L-2-hydroxy fatty acid + NAD+
2-keto fatty acid + NADH + H+
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Substrates: intermediate product in the alpha-oxidation of normal and/or branched long-chain fatty acids Products: -
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L-2-hydroxystearate + NAD+
2-oxostearate + NADH + H+
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Substrates: - Products: -
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three different forms: HAOX1, HAOX2, HAOX3
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HAOX1 and HAOX2
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HAOX1 and, exclusively, HAOX3
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HAOX2
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Highest Expressing Human Cell Lines
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Cell Line Links
Gene Links
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additional information
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overexpression of HAOX1, HAOX2, HAOX3 in Escherichia coli strain DH10B as His-tagged proteins and in human skin fibroblasts GM5756-T cells as c-myc-tagged proteins
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three different genes, HAOX1, HAOX2, HAOX3, coding for 3 different 2-hydroxy acid oxidases, overexpression in Escherichia coli strain DH10B as His-tagged protein and in human skin fibroblasts GM5756-T cells as c-myc-tagged protein
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Levis, G.M.
2-Hydroxy fatty acid oxidases of rat kidney
Biochem. Biophys. Res. Commun.
38
470-477
1970
Rattus norvegicus
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Jones, J.M.; Morrell, J.C.; Gould, S.J.
Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases
J. Biol. Chem.
275
12590-12597
2000
Homo sapiens
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