2.5.1.30: heptaprenyl diphosphate synthase
This is an abbreviated version!
For detailed information about heptaprenyl diphosphate synthase, go to the full flat file.
Word Map on EC 2.5.1.30
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2.5.1.30
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prenyltransferase
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allylic
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synthases
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menaquinone-7
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stearothermophilus
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geranylgeranyl
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hexaprenyl
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medium-chain
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micrococcus
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luteus
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heteromeric
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hepes
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mops
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zwitterionic
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undecaprenyl
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pharmacology
- 2.5.1.30
- prenyltransferase
-
allylic
- synthases
- menaquinone-7
- stearothermophilus
-
geranylgeranyl
-
hexaprenyl
-
medium-chain
-
micrococcus
- luteus
-
heteromeric
- hepes
- mops
-
zwitterionic
- undecaprenyl
- pharmacology
Reaction
+ 4 isopentenyl diphosphate = 4 diphosphate +
Synonyms
HepPP synthase, HepPPS, HepPS, heptaprenyl pyrophosphate synthetase, heptaprenylpyrophosphate synthetase
ECTree
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Inhibitors
Inhibitors on EC 2.5.1.30 - heptaprenyl diphosphate synthase
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(2-[3'-[([1,1'-biphenyl]-4-sulfonyl)amino][1,1'-biphenyl]-3-yl]-1-hydroxyethane-1,1-diyl)bis(phosphonic acid)
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1-dodecyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium
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3-(2,2-diphosphonoethyl)-1-(4-methoxyphenyl)-1H-imidazol-3-ium
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3-(2-hydroxy-2,2-diphosphonoethyl)-1-pentadecyl-1H-imidazol-3-ium
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3-(2-hydroxy-2,2-diphosphonoethyl)-1-tetradecyl-1H-imidazol-3-ium
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3-(2-hydroxy-2,2-diphosphonoethyl)-1-undecyl-1H-imidazol-3-ium
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[2-[5-(decyloxy)pyridin-3-yl]ethane-1,1-diyl]bis(phosphonic acid)
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enzymatic activity is inhibited by each antiserum against component I or component II, indicating that either component I or component II is confirmed immunochemically to be essential for enzymatic activity
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additional information
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enzymatic activity is inhibited by each antiserum against component I or component II, indicating that either component I or component II is confirmed immunochemically to be essential for enzymatic activity
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additional information
the most active inhibitors (Ki about 200 nM) are N-alkyl analogs of zoledronate containing C6 alkyl side-chains
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additional information
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the most active inhibitors (Ki about 200 nM) are N-alkyl analogs of zoledronate containing C6 alkyl side-chains
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