2.1.1.218: tRNA (adenine9-N1)-methyltransferase
This is an abbreviated version!
For detailed information about tRNA (adenine9-N1)-methyltransferase, go to the full flat file.
Reaction
Synonyms
adenosine-specific Trm10, EC 2.1.1.36, hTRMT10B, m1A9 MTase, m1R9-specific TkTrm10, More, SaTrm10, SPOUT MTase, TK0422p, TkTrm10, Trm10, Trm10p (ambiguous), TRMT10B, Trmt10C, tRNA m1A9 methyltransferase, tRNA m1A9 MTase, tRNA m1A9-methyltransferase, tRNA m1R9 methyltransferase, tRNA(m1G9/m1A9)-methyltransferase, tRNA(m1G9/m1A9)MTase
ECTree
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Metals Ions
Metals Ions on EC 2.1.1.218 - tRNA (adenine9-N1)-methyltransferase
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Mg2+
additional information
no activity is detected in the absence of metal
Mg2+
required, the two tRNAs from Saccharomyces cerevisiae requires a much higher Mg2+ concentration (6-10 mM in the assay) for maximal TkTrm10 activity compared to the two Thermococcus kodakarensis tRNAs, for which maximal activity is observed at about 1 mM Mg2+ or less. Similar trends are exhibited for both m1G9 and m1A9 reactions, indicating that the identity of the target purine does not affect the observed metal dependencies