1.20.99.1: arsenate reductase (donor)
This is an abbreviated version!
For detailed information about arsenate reductase (donor), go to the full flat file.
Word Map on EC 1.20.99.1
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1.20.99.1
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arsenite
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asiii
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dissimilatory
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shewanella
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geobacter
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groundwater
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selenate
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paddy
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biogeochemical
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arsenic-rich
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haloalkaliphile
- 1.20.99.1
- arsenite
-
asiii
-
dissimilatory
- shewanella
- geobacter
-
groundwater
- selenate
-
paddy
-
biogeochemical
-
arsenic-rich
-
haloalkaliphile
Reaction
Synonyms
Acr2, ACR2.1, ACR2.2, AR, Arr, ArrA, ArsC, arsenate reductase, arsenite oxidase, As(V) reductase, ATQ1, Cdc25B, Cdc25C, EC 1.97.1.6, gene arsC proteins, HAC1, More, proteins (specific proteins and subclasses), genearsC, reductase, arsenate, respiratory arsenate reductase
ECTree
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General Information
General Information on EC 1.20.99.1 - arsenate reductase (donor)
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malfunction
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plants lacking the enzyme lose their ability to efflux arsenite from roots, leading to both increased transport of arsenic into the central vascular tissue and on into the shoot. Loss of enzyme-encoded arsenic reduction leads to a significant increase in arsenic accumulation in shoots, causing an increased sensitivity to arsenate toxicity
metabolism
physiological function
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anaerobic growth of Pseudomonas putida WB on glucose is shown by arsenate reductase ArsC with energy derived only from substrate level phosphorylation. Two mol of acetate are generated intermediary and the reducing equivalents of glycolysis and pyruvate decarboxylation serve for arsenate reduction or are released as H2
metabolism
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anaerobic growth on acetate and lactate is shown by arsenate reductase ArrA coupled to respiratory electron chain energy conservation. In the presence of arsenate, both substrates are totally oxidized to CO2 and H2 with part of the H2 serving for respiratory arsenate reduction to deliver energy for growth
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the enzyme functions to reduce arsenate to arsenite in the outer cell layer of the root, facilitating efflux of arsenic as arsenite back into the soil to limit both its accumulation in the root and transport to the shoot. Arsenate reduction by the enzyme in the pericycle may play a role in limiting arsenic loading into the xylem
physiological function
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the enzyme is necessary for the efflux of arsenite from roots required for arsenate detoxification