1.14.99.60: 3-demethoxyubiquinol 3-hydroxylase
This is an abbreviated version!
For detailed information about 3-demethoxyubiquinol 3-hydroxylase, go to the full flat file.
Word Map on EC 1.14.99.60
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1.14.99.60
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elegans
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lifespan
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nematode
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longevity
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ubiquinone
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worm
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long-lived
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demethoxyubiquinone
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dauer
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life-extending
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coq
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defecation
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gerontogenes
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analysis
- 1.14.99.60
- elegans
-
lifespan
- nematode
-
longevity
- ubiquinone
-
worm
-
long-lived
-
demethoxyubiquinone
-
dauer
-
life-extending
- coq
-
defecation
-
gerontogenes
- analysis
Reaction
Synonyms
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase, 6-methoxy-3-methyl-2-(all-trans-polyprenyl)-1,4-benzoquinol 5-hydroxylase, Cat5, clk-1, CLK1, COQ7, ubiF
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Substrates Products
Substrates Products on EC 1.14.99.60 - 3-demethoxyubiquinol 3-hydroxylase
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REACTION DIAGRAM
6-methoxy-3-methyl-2-(all-trans-polyprenyl)-1,4-benzoquinol + a reduced acceptor + O2
3-demethylubiquinol + acceptor + H2O
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6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen
3-demethylubiquinol-8 + H2O + an oxidized electron acceptor
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?
6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen
an oxidized electron acceptor + 3-demethylubiquinol-8 + H2O
an oxidized electron acceptor + 3-demethylubiquinol-8 + H2O
the enzyme catalyzes a reaction in the ubiquinone biosynthesis pathway
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6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen
an oxidized electron acceptor + 3-demethylubiquinol-8 + H2O
the ubiF mutant accumulates 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone. The enzyme has not been characterized biochemically
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