EC 1.1.1.394: aurachin B dehydrogenase

This is an abbreviated version!
For detailed information about aurachin B dehydrogenase, go to the full flat file.

Reaction

Synonyms

AuaH

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.394 aurachin B dehydrogenase

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All data fields related to EC 1.1.1.394

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1	AA Sequence
1	Cloned(Commentary)
1	Cofactor
4	General Information
2	Natural Substrates/ Products (Substrates)
2	Organism
3	Pathway
1	Purification (Commentary)
5	Reaction
2	Reference
2	Substrates and Products (Substrate)
2	Subunits
3	Synonyms
1	Systematic Name

Systematic Name

Systematic Name on EC 1.1.1.394 - aurachin B dehydrogenase

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SYSTEMATIC NAME

IUBMB Comments

aurachin B:NAD+ 3-oxidoreductase

The enzyme from the bacterium Stigmatella aurantiaca catalyses the final step in the conversion of aurachin C to aurachin B. In vivo the enzyme catalyses the reduction of 4-[(2E,6E)-farnesyl]-4-hydroxy-2-methyl-3-oxo-3,4-dihydroquinoline-1-oxide to form 4-[(2E,6E)-farnesyl]-2-methyl-1-oxo-3,4-dihydroquinoline-3,4-diol (note that the reactions written above proceed from right to left), which then undergoes a spontaneous dehydration to form aurachin B.