Reference on EC 2.7.1.82 - ethanolamine kinase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Faulkner, A.; Turner, J.M.
Phosphorylation of ethanolamine in catabolism. Biodegradative adenosine triphosphate-ethanolamine phosphotransferase and related enzymes in bacteria
Biochem. Soc. Trans.
2
133-136
1974
Achromobacter sp., Flavobacterium rhenanum, Microbacterium arborescens
-
Ishidate, K.; Furusawa, K.; Nakazawa, Y.
Complete co-purification of choline kinase and ethanolamine kinase from rat kidney and immunological evidence for both kinase activities residing on the same enzyme protein(s) in rat tissues
Biochim. Biophys. Acta
836
119-124
1985
BRENDA: Rattus norvegicus
Textmining: Rattus, Oryctolagus cuniculus
Upreti, R.K.; Sanwal, G.G.; Krishnan, P.S.
Likely individuality of the enzymes catalyzing the phosphorylation of choline and ethanolamine
Arch. Biochem. Biophys.
174
658-665
1976
Duttaphrynus melanostictus, Capra hircus, Cavia porcellus, Gallus gallus, Columba livia, Hemidactylus sp., Heteropneustes fossilis, Mus musculus, Hoplobatrachus tigerinus, Rattus norvegicus
Brophy, P.J.; Choy, P.C.; Toone, J.R.; Vance, D.E.
Choline kinase and ethanolamine kinase are separate, soluble enzymes in rat liver
Eur. J. Biochem.
78
491-495
1977
BRENDA: Rattus norvegicus
Textmining: Rattus
Weinhold, P.A.; Rethy, V.B.
The separation, purification, and characterization of ethanolamine kinase and choline kinase from rat liver
Biochemistry
13
5135-5141
1974
BRENDA: Rattus norvegicus
Textmining: Rattus
Spanner, S.; Ansell, G.B.
Choline kinase and ethanolamine kinase activity in the cytoplasm of nerve endings from rat forebrain
Biochem. Soc. Trans.
5
164-165
1977
BRENDA: Rattus norvegicus
Textmining: Rattus
Ramabrahmam, P.; Subrahmanyam, D.
Ethanolamine kinase from Culex pipiens fatigans
Arch. Biochem. Biophys.
207
55-62
1981
Culex quinquefasciatus
Infante, J.P.; Kinsella, J.E.
Phospholipid synthesis in mammary tissue. Choline and ethanolamine kinases: kinetic evidence for two discrete active sites
Lipids
11
727-735
1976
Bos taurus
Shelley, R.M.; Hodgson, E.
Substrate specificity and inhibition of choline and ethanolamine kinases from the fat body of Phormia rigina larvae
Insect Biochem.
1
149-156
1971
Phormia regina
-
Porter, T.J.; Kent, C.
Purification and characterization of choline/ethanolamine kinase from rat liver
J. Biol. Chem.
265
414-422
1990
Rattus
Aoyama, C.; Ohtani, A.; Ishidate, K.
Expression and characterization of the active molecular forms of choline/ethanolamine kinase-alpha and -beta in mouse tissues, including carbon tetrachloride-induced liver
Biochem. J.
363
777-784
2002
Mus musculus
Ishidate, K.
Choline/ethanolamine kinase from mammalian tissues
Biochim. Biophys. Acta
1348
70-78
1997
Saccharomyces cerevisiae, Homo sapiens, Rattus norvegicus
Liu, Y.; Ekambaram, M.C.; Blum, P.S.; Stimbert, C.D.; Jernigan, H.M., Jr.
Galactosemic cataractogenesis disrupts intracellular interactions and changes the substrate specificity of choline/ethanolamine kinase
Exp. Eye Res.
67
193-202
1998
BRENDA: Rattus norvegicus
Textmining: Homo sapiens, Canis lupus familiaris, Rattus, Platyrrhini, Suidae, Oryctolagus cuniculus
Aoyama, C.; Yamazaki, N.; Terada, H.; Ishidate, K.
Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta
J. Lipid Res.
41
452-464
2000
Mus musculus (O54804), Mus musculus (Q54AG5), Mus musculus (Q9D4V0)
Sung, C.P.; Johnstone, R.M.
Phosphorylation of choline and ethanolamine in Ehrlich ascites-carcinoma cells
Biochem. J.
105
497-503
1967
Mus musculus
Weinhold, P.A.; Rethy, V.B.
Ethanolamine phosphokinase: activity and properties during liver development
Biochim. Biophys. Acta
276
143-154
1972
Rattus norvegicus
Wharfe, J.; Harwood, J.L.
Lipid metabolism in germinating seeds. Purification of ethanolamine kinase from soya bean
Biochim. Biophys. Acta
575
102-111
1979
Glycine max
Draus, E.; Niefield, J.; Vietor, K.; Havsteen, B.
Isolation and characterization of the human liver ethanolamine kinase
Biochim. Biophys. Acta
1045
195-204
1990
Homo sapiens
Macher, B.A.; Mudd, J.B.
Partial purification and properties of ethanolamine kinase from spinach leaf
Arch. Biochem. Biophys.
177
24-30
1976
Spinacia oleracea
Lykidis, A.; Wang, J.; Karim, M.A.; Jackowski, S.
Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway
J. Biol. Chem.
276
2174-2179
2001
BRENDA: Homo sapiens (Q9HBU6), Homo sapiens
Textmining: Mammalia
Kim, K.; Kim, K.H.; Storey, M.K.; Voelker, D.R.; Carman, G.M.
Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase
J. Biol. Chem.
274
14857-14866
1999
BRENDA: Saccharomyces cerevisiae
Textmining: Saccharomyces
Nyako, M.; Marks, C.; Sherma, J.; Reynolds, E.R.
Tissue-specific and developmental effects of the easily shocked mutation on ethanolamine kinase activity and phospholipid composition in Drosophila melanogaster
Biochem. Genet.
39
339-349
2001
BRENDA: Drosophila melanogaster
Textmining: Diptera, Drosophila
Uchida, T.
A novel high-molecular mass mammalian ethanolamine kinase
Biochim. Biophys. Acta
1349
13-24
1997
BRENDA: Rattus norvegicus
Textmining: Escherichia coli, Drosophila, Homo sapiens, Rattus, plant
Pascual, A.; Chaminade, M.; Preat, T.
Ethanolamine kinase controls neuroblast divisions in Drosophila mushroom bodies
Dev. Biol.
280
177-186
2005
BRENDA: Drosophila melanogaster
Textmining: Drosophila
Kersting, M.C.; Choi, H.S.; Carman, G.M.
Regulation of the yeast EKI1-encoded ethanolamine kinase by inositol and choline
J. Biol. Chem.
279
35353-35359
2004
Saccharomyces cerevisiae
Kersting, M.C.; Carman, G.M.
Regulation of the Saccharomyces cerevisiae EKI1-encoded ethanolamine kinase by zinc depletion
J. Biol. Chem.
281
13110-13116
2006
Saccharomyces cerevisiae
Tian, Y.; Jackson, P.; Gunter, C.; Wang, J.; Rock, C.O.; Jackowski, S.
Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2
J. Biol. Chem.
281
28438-28449
2006
BRENDA: Mus musculus (A7MCT6)
Textmining: Metazoa, Mus sp.
Gibellini, F.; Hunter, W.N.; Smith, T.K.
Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinases
Biochem. J.
415
135-144
2008
Trypanosoma brucei (Q386V0), Trypanosoma brucei (Q57W59), Trypanosoma brucei
Gustin, S.E.; Western, P.S.; McClive, P.J.; Harley, V.R.; Koopman, P.A.; Sinclair, A.H.
Testis development, fertility, and survival in ethanolamine kinase 2-deficient mice
Endocrinology
149
6176-6186
2008
BRENDA: Mus musculus
Textmining: Mus sp.
Signorell, A.; Jelk, J.; Rauch, M.; Buetikofer, P.
Phosphatidylethanolamine is the precursor of the ethanolamine phosphoglycerol moiety bound to eukaryotic elongation factor 1A
J. Biol. Chem.
283
20320-20329
2008
Trypanosoma brucei
Ding, S.T.; Yen, C.F.; Wang, P.H.; Lin, H.W.; Hsu, J.C.; Shen, T.F.
The differential expression of hepatic genes between prelaying and laying geese
Poult. Sci.
86
1206-1212
2007
BRENDA: Anser sp.
Textmining: Anser
Alberge, B.; Gannoun-Zaki, L.; Bascunana, C.; Tran van Ba, C.; Vial, H.; Cerdan, R.
Comparison of the cellular and biochemical properties of Plasmodium falciparum choline and ethanolamine kinases
Biochem. J.
425
149-158
2010
BRENDA: Plasmodium falciparum (Q8IIB7), Plasmodium falciparum, Plasmodium falciparum 3D7 (Q8IIB7)
Textmining: Escherichia coli
Lasho, T.L.; Finke, C.M.; Zblewski, D.; Patnaik, M.; Ketterling, R.P.; Chen, D.; Hanson, C.A.; Tefferi, A.; Pardanani, A.
Novel recurrent mutations in ethanolamine kinase 1 (ETNK1) gene in systemic mastocytosis with eosinophilia and chronic myelomonocytic leukemia
Blood Cancer J.
5
e275
2015
Homo sapiens (Q9HBU6), Homo sapiens
He, R.; Guo, W.; Zhang, D.
An ethanolamine kinase Eki1 affects radial growth and cell wall integrity in Trichoderma reesei
FEMS Microbiol. Lett.
362
fnv133
2015
BRENDA: Trichoderma reesei, Trichoderma reesei QM9414
Textmining: Saccharomyces cerevisiae, Tephritidae, Fungi
Ling, C.S.; Yin, K.B.; Cun, S.T.; Ling, F.L.
Expression profiling of choline and ethanolamine kinases in MCF7, HCT116 and HepG2 cells, and the transcriptional regulation by epigenetic modification
Mol. Med. Rep.
11
611-618
2015
BRENDA: Homo sapiens (Q9HBU6), Homo sapiens (Q9NVF9)
Textmining: Transformation
Lin, Y.C.; Liu, Y.C.; Nakamura, Y.
The choline/ethanolamine kinase family in Arabidopsis: essential role of CEK4 in phospholipid biosynthesis and embryo development
Plant Cell
27
1497-1511
2015
Arabidopsis thaliana (O81024)
Kuan, C.S.; See Too, W.C.; Few, L.L.
Sp1 and Sp3 are the transcription activators of human ek1 promoter in TSA-treated human colon carcinoma cells
PLoS ONE
11
e0147886
2016
Homo sapiens (Q9HBU6), Homo sapiens
Lin, Y.C.; Araguirang, G.E.; Ngo, A.H.; Lin, K.T.; Angkawijaya, A.E.; Nakamura, Y.
The four Arabidopsis choline/ethanolamine kinase isozymes play distinct roles in metabolism and development
Plant Physiol.
183
152-166
2020
Arabidopsis thaliana (O81024)
Zhou, X; Weatherford, ET; Liu, X; Born, E; Keen, HL; Sigmund, CD
Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus.
Am J Physiol Renal Physiol
295
F642-53
2008
Homo sapiens, Mus musculus
Spanner, S; Ansell, GB
Choline kinase and ethanolamine kinase activity in the cytosol of nerve endings from rat forebrain.
Biochem J
178
753-60
1979
Rattus
Brophy, PJ; Vance, DE
Copurification of choline kinase and ethanolamine kinase from rat liver by affinity chromatography.
FEBS Lett
62
123-5
1976
Rattus
Hosaka, K; Kodaki, T; Yamashita, S
Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli.
J Biol Chem
264
2053-9
1989
Saccharomyces cerevisiae
Monks, DE; Goode, JH; Dewey, RE
Characterization of soybean choline kinase cDNAs and their expression in yeast and Escherichia coli.
Plant Physiol
110
1197-205
1996
Glycine max
Serrán-Aguilera, L; Denton, H; Rubio-Ruiz, B; López-Gutiérrez, B; Entrena, A; Izquierdo, L; Smith, TK; Conejo-García, A; Hurtado-Guerrero, R
Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death.
Sci Rep
6
33189
2016
Plasmodium falciparum
Spanner, S; Ansell, GB
Choline and ethanolamine kinase activity in the cytoplasm of nerve endings from rat forebrain.
Adv Exp Med Biol
101
237-45
1978
Rattus
Tinoco, J; Endemann, G; Medwadowski, B; Miljanich, P; Williams, MA
Ethanolamine kinase activity and compositions of diacylglycerols, phosphatidylcholines and phosphatidylethanolamines in livers of choline-deficient rats.
Lipids
14
968-74
1979
Rattus
Infante, JP; Kinsella, JE
Co-ordinate regulation of ethanolamine kinase and phosphoethanolamine cytidylyltransferase in the biosynthesis of phosphatidylethanolamine in rat liver.
Biochem J
179
723-5
1979
Rattus
Kunishita, T; Vaswani, KK; Morrow, CR; Novak, GP; Ledeen, RW
Ethanolamine kinase activity in purified myelin of rat brain.
J Neurochem
48
1-7
1987
Rattus
Xing, Y; Xu, C; Lin, X; Zhao, M; Gong, D; Liu, L; Geng, T
Complement C3 participates in the development of goose fatty liver potentially by regulating the expression of FASN and ETNK1.
Anim Sci J
92
e13527
2021
Anser sp.
Ishidate, K; Tsuruoka, M; Nakazawa, Y
Alteration in enzyme activities of de novo phosphatidylcholine biosynthesis in rat liver by treatment with typical inducers of microsomal drug-metabolizing system.
Biochim Biophys Acta
620
49-58
1980
Rattus, animal
Ross, BM; Eder, K; Moszczynska, A; Mamalias, N; Lamarche, J; Ang, L; Pandolfo, M; Rouleau, G; Kirchgessner, M; Kish, SJ
Abnormal activity of membrane phospholipid synthetic enzymes in the brain of patients with Friedreich's ataxia and spinocerebellar atrophy type-1.
Mov Disord
15
294-300
2000
Homo sapiens, Areas
Wang, J; Liu, Y; Cheng, X; Zhang, X; Liu, F; Liu, G; Qiao, S; Ni, M; Zhou, W; Zhang, Y; Li, F
The Effects of LW-AFC on the Hippocampal Transcriptome in Senescence-Accelerated Mouse Prone 8 Strain, a Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
57
227-240
2017
Mus sp., Hippocampus
Schneider, WJ; Vance, DE
Effect of choline deficiency on the enzymes that synthesize phosphatidylcholine and phosphatidylethanolamine in rat liver.
Eur J Biochem
85
181-7
1978
Rattus
Upreti, RK
Influence of choline and ethanolamine administration on choline and ethanolamine phosphorylating activities of mouse liver and kidney.
Can J Biochem
57
981-5
1979
Mus sp.
Ishidate, K; Iida, K; Tadokoro, K; Nakazawa, Y
Evidence for the existence of multiple forms of choline (ethanolamine) kinase in rat tissues.
Biochim Biophys Acta
833
1-8
1985
Rattus
Ancelin, ML; Vial, HJ
Several lines of evidence demonstrating that Plasmodium falciparum, a parasitic organism, has distinct enzymes for the phosphorylation of choline and ethanolamine.
FEBS Lett
202
217-23
1986
Plasmodium, Plasmodium falciparum
Upreti, RK
Age dependent variations in choline and ethanolamine phosphorylating activities of rodents.
Biochem Exp Biol
16
221-6
1980
Mus musculus, Rattus, Rodentia, animal
Pu, GA; Anderson, RE
Ethanolamine accumulation by photoreceptor cells of the rabbit retina.
J Neurochem
42
185-91
1984
Oryctolagus cuniculus
Ekambaram, MC; Jernigan, HM
Rat lens choline and ethanolamine kinases: independent kinetics in intact tissue-competition in homogenates.
Biochim Biophys Acta
1213
289-94
1994
Rattus
Ross, BM; Moszczynska, A; Blusztajn, JK; Sherwin, A; Lozano, A; Kish, SJ
Phospholipid biosynthetic enzymes in human brain.
Lipids
32
351-8
1997
Homo sapiens
Upreti, RK; Shanker, R
Effect of oral ethanol administration on choline and ethanolamine phosphorylating activities in liver and brain of mice.
Toxicology
11
297-302
1978
Mus sp.
Houweling, M; Tijburg, LB; Vaartjes, WJ; van Golde, LM
Phosphatidylethanolamine metabolism in rat liver after partial hepatectomy. Control of biosynthesis of phosphatidylethanolamine by the availability of ethanolamine.
Biochem J
283 ( Pt 1)
55-61
1992
Rattus, Metazoa
Pavlidis, P; Ramaswami, M; Tanouye, MA
The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis.
Cell
79
23-33
1994
Transformation, Drosophila, Diptera
Tang, F; Moore Jr, TS
Enzymes of the Primary Phosphatidylethanolamine Biosynthetic Pathway in Postgermination Castor Bean Endosperm (Developmental Profiles and Partial Purification of the Mitochondrial CTP:Ethanolaminephosphate Cytidylyltransferase).
Plant Physiol
115
1589-1597
1997
Ricinus communis
Kliman, M; Vijayakrishnan, N; Wang, L; Tapp, JT; Broadie, K; McLean, JA
Structural mass spectrometry analysis of lipid changes in a Drosophila epilepsy model brain.
Mol Biosyst
2010
Drosophila, animal
Kroll, JR; Tanouye, MA
Rescue of easily shocked mutant seizure sensitivity in drosophila adults.
J Comp Neurol
521
3500-7
2013
Drosophila, Diptera
Malewicz, B; Mukherjee, JJ; Crilly, KS; Baumann, WJ; Kiss, Z
Phosphorylation of ethanolamine, methylethanolamine, and dimethylethanolamine by overexpressed ethanolamine kinase in NIH 3T3 cells decreases the co-mitogenic effects of ethanolamines and promotes cell survival.
Eur J Biochem
253
10-9
1998
Drosophila
Miwa, T; Kanda, M; Shimizu, D; Umeda, S; Sawaki, K; Tanaka, H; Tanaka, C; Hattori, N; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Kodera, Y
Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53-Bcl-2 intrinsic apoptosis pathway.
Br J Cancer
124
1449-1460
2021
Homo sapiens, Mus musculus
Han, X; Tan, Q; Yang, S; Li, J; Xu, J; Hao, X; Hu, X; Xing, P; Liu, Y; Lin, L; Gui, L; Qin, Y; Yang, J; Liu, P; Wang, X; Dai, W; Lin, D; Lin, H; Shi, Y
Comprehensive Profiling of Gene Copy Number Alterations Predicts Patient Prognosis in Resected Stages I-III Lung Adenocarcinoma.
Front Oncol
9
556
2019
Homo sapiens
Upreti, RK
Search for sex-dependent and gestation-induced changes in choline and ethanolamine phosphorylating activities.
Experientia
34
166-7
1978
Mus sp.
Gómez-Pérez, V; Manzano, JI; García-Hernández, R; Castanys, S; Gamarro, F; Campos, JM
Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.
Eur J Med Chem
89
362-9
2015
Leishmania
Lim, HY; Bodmer, R
Phospholipid homeostasis and lipotoxic cardiomyopathy: A matter of balance.
Fly (Austin)
5
234-6
2011
Drosophila
Kwon, YJ; Heo, J; Wong, HE; Cruz, DJ; Velumani, S; da Silva, CT; Mosimann, AL; Duarte Dos Santos, CN; Freitas-Junior, LH; Fink, K
Kinome siRNA screen identifies novel cell-type specific dengue host target genes.
Antiviral Res
110
20-30
2014
Homo sapiens, Dengue virus
Fu, G; Guy, CS; Chapman, NM; Palacios, G; Wei, J; Zhou, P; Long, L; Wang, YD; Qian, C; Dhungana, Y; Huang, H; Kc, A; Shi, H; Rankin, S; Brown, SA; Johnson, A; Wakefield, R; Robinson, CG; Liu, X; Sheyn, A; Yu, J; Jackowski, S; Chi, H
Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine.
Nature
595
724-729
2021
Mus sp.
html completed
