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2.3.3.17: methylthioalkylmalate synthase

This is an abbreviated version!
For detailed information about methylthioalkylmalate synthase, go to the full flat file.

Word Map on EC 2.3.3.17

Reaction

an omega-(methylsulfanyl)-2-oxoalkanoate
+
acetyl-CoA
 +
H2O
=
a 2-[omega-(methylsulfanyl)alkyl]malate
 +
CoA

Synonyms

MAM, MAM synthase, MAM1, MAM2, MAM3, MAMS, methylthioalkylmalate synthase 1, methylthioalkylmalate synthase1

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.3 Acyl groups converted into alkyl groups on transfer
                2.3.3.17 methylthioalkylmalate synthase

KCat KM Value

KCat KM Value on EC 2.3.3.17 - methylthioalkylmalate synthase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.2
2-oxoisovalerate
at pH 8.0 and 32°C
1.38
4-methylthio-2-oxobutanoate
at pH 8.0 and 32°C
2.73
5-methylthio-2-oxopentanoate
at pH 8.0 and 32°C
5.4
6-methylthio-2-oxohexanoate
at pH 8.0 and 32°C
1.28
8-methylthio-2-oxooctanoate
at pH 8.0 and 32°C
0.37
9-methylthio-2-oxononanoate
at pH 8.0 and 32°C
1.3
acetyl-CoA
at pH 8.0 and 32°C
0.023
pyruvate
at pH 8.0 and 32°C