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Sequence of TBG1_HUMAN

EC Number:3.6.5.6

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tubulin GTPase
P23258
Homo sapiens
451
51170
Reaction
GTP + H2O = GDP + phosphate
Other sequences found for EC No. 3.6.5.6

General information:

Sequence
show sequence in fasta format
  0 MPREIITLQL GQCGNQIGFE FWKQLCAEHG ISPEGIVEEF ATEGTDRKDV FFYQADDEHY
 60 IPRAVLLDLE PRVIHSILNS PYAKLYNPEN IYLSEHGGGA GNNWASGFSQ GEKIHEDIFD
120 IIDREADGSD SLEGFVLCHS IAGGTGSGLG SYLLERLNDR YPKKLVQTYS VFPNQDEMSD
180 VVVQPYNSLL TLKRLTQNAD CVVVLDNTAL NRIATDRLHI QNPSFSQINQ LVSTIMSAST
240 TTLRYPGYMN NDLIGLIASL IPTPRLHFLM TGYTPLTTDQ SVASVRKTTV LDVMRRLLQP
300 KNVMVSTGRD RQTNHCYIAI LNIIQGEVDP TQVHKSLQRI RERKLANFIP WGPASIQVAL
360 SRKSPYLPSA HRVSGLMMAN HTSISSLFER TCRQYDKLRK REAFLEQFRK EDMFKDNFDE
420 MDTSREIVQQ LIDEYHAATR PDYISWGTQE Q
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
239345
Zheng Y.,Jung M.K.,Oakley B.R.
Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome.
Cell
65
817-823
1991
239348
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
239349
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
239350
Harris R.A.,Yang A.,Stein R.C.,Lucy K.,Brusten L.,Herath A.,Parekh R.,Waterfield M.D.,O'Hare M.J.,Neville M.A.,Page M.J.,Zvelebil M.J.
Cluster analysis of an extensive human breast cancer cell line protein expression map database.
Proteomics
2
212-223
2002
239351
Murphy S.M.,Urbani L.,Stearns T.
The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p.
J. Cell Biol.
141
663-674
1998
239352
Tassin A.-M.,Celati C.,Moudjou M.,Bornens M.
Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.
J. Cell Biol.
141
689-701
1998
239353
Andersen J.S.,Wilkinson C.J.,Mayor T.,Mortensen P.,Nigg E.A.,Mann M.
Proteomic characterization of the human centrosome by protein correlation profiling.
Nature
426
570-574
2003
239354
Fong K.W.,Choi Y.K.,Rattner J.B.,Qi R.Z.
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex.
Mol. Biol. Cell
19
115-125
2008
239355
Kinzel D.,Boldt K.,Davis E.E.,Burtscher I.,Trumbach D.,Diplas B.,Attie-Bitach T.,Wurst W.,Katsanis N.,Ueffing M.,Lickert H.
Pitchfork regulates primary cilia disassembly and left-right asymmetry.
Dev. Cell
19
66-77
2010
239356
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
239357
Hashizume C.,Moyori A.,Kobayashi A.,Yamakoshi N.,Endo A.,Wong R.W.
Nucleoporin Nup62 maintains centrosome homeostasis.
Cell Cycle
12
3804-3816
2013
239358
Luo J.,Yang B.,Xin G.,Sun M.,Zhang B.,Guo X.,Jiang Q.,Zhang C.
The microtubule-associated protein EML3 regulates mitotic spindle assembly by recruiting the Augmin complex to spindle microtubules.
J. Biol. Chem.
294
5643-5656
2019
239359
Poirier K.,Lebrun N.,Broix L.,Tian G.,Saillour Y.,Boscheron C.,Parrini E.,Valence S.,Pierre B.S.,Oger M.,Lacombe D.,Genevieve D.,Fontana E.,Darra F.,Cances C.,Barth M.,Bonneau D.,Bernadina B.D.,N'guyen S.,Gitiaux C.,Parent P.,des Portes V.,Pedespan J.M.,Legrez V.,Castelnau-Ptakine L.,Nitschke P.,Hieu T.,Masson C.,Zelenika D.,Andrieux A.,Francis F.,Guerrini R.,Cowan N.J.,Bahi-Buisson N.,Chelly J.
Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly.
Nat. Genet.
45
639-647
2013