Sequence of KANK_STRKN
EC Number:1.1.1.355
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
kanamycin A + NADP+ = 2'-dehydrokanamycin A + NADPH + H+
Other sequences found for EC No. 1.1.1.355
General information:
Sequence
0 MSSQLALRGP ELSANLCKPE EDTLRVLVTG GSGNVGVGVV RALNAARHHV VVASRGYSPA
60 LLPEGVRAVR LERTEPDAYT RLVAAEKPDA VIDLTCHDAA DAAVTLRACA GVDRVVVVSS
120 VTAAGPATTT PVTEATAAPP LSEYGIDKLA VEETVRAAWA DGTSQALLVR LGAVYRLGAD
180 LDGQLAEDGC WLAHAAAGAP AVLADDGAAR WNLLHADDAG AALAELLAND RARGVLVHLA
240 SRHPLPWREL YERVHHALGR PFNPVSVPAE WAAEQLEDAE FLAETSRWDQ VFDLGLLDRL
300 APSYQERGGP SRVTEVALWL IRQGRVGDAE LGAEIQELPA RLAAVRTAPG LV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1075160
Kharel M.K.,Subba B.,Basnet D.B.,Woo J.S.,Lee H.C.,Liou K.,Sohng J.K.
A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster.
Arch. Biochem. Biophys.
429
204-214
2004
1075161
Yanai K.,Murakami T.
The kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus.
J. Antibiot.
57
351-354
2004
1075163
Sucipto H.,Kudo F.,Eguchi T.
The last step of kanamycin biosynthesis: unique deamination reaction catalyzed by the alpha-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK.
Angew. Chem. Int. Ed.
51
3428-3431
2012
