Sequence of CEGT_MOUSE
EC Number:2.4.1.80
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
UDP-alpha-D-glucose + an N-acylsphingosine = UDP + a beta-D-glucosyl-N-acylsphingosine
Other sequences found for EC No. 2.4.1.80
General information:
Sequence
0 MALLDLAQEG MALFGFVLFV VLWLMHFMSI IYTRLHLNKK ATDKQPYSKL PGVSLLKPLK
60 GVDPNLINNL ETFFELDYPK YEVLLCVQDH DDPAIDVCKK LLGKYPNVDA RLFIGGKKVG
120 INPKINNLMP AYEVAKYDLI WICDSGIRVI PDTLTDMVNQ MTEKVGLVHG LPYVADRQGF
180 AATLEQVYFG TSHPRSYISA NVTGFKCVTG MSCLMRKDVL DQAGGLIAFA QYIAEDYFMA
240 KAIADRGWRF SMSTQVAMQN SGSYSISQFQ SRMIRWTKLR INMLPATIIC EPISECFVAS
300 LIIGWAAHHV FRWDIMVFFM CHCLAWFIFD YIQLRGVQGG TLCFSKLDYA VAWFIRESMT
360 IYIFLSALWD PTISWRTGRY RLRCGGTAEE ILDV
Download this sequence
in fasta formatDownload all sequences for 2.4.1.80
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1039682
Ichikawa S.,Ozawa K.,Hirabayashi Y.
Molecular cloning and characterization of the mouse ceramide glucosyltransferase gene.
Biochem. Biophys. Res. Commun.
253
707-711
1998
1039683
Ichikawa S.,Ozawa K.,Hirabayashi Y.
Molecular cloning and expression of mouse ceramide glucosyltransferase.
Biochem. Mol. Biol. Int.
44
1193-1202
1998
1039684
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
0-0
2009
1039686
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1039687
Yamashita T.,Wada R.,Sasaki T.,Deng C.,Bierfreund U.,Sandhoff K.,Proia R.L.
A vital role for glycosphingolipid synthesis during development and differentiation.
Proc. Natl. Acad. Sci. U.S.A.
96
9142-9147
1999
1039688
Yamashita T.,Wada R.,Proia R.L.
Early developmental expression of the gene encoding glucosylceramide synthase, the enzyme controlling the first committed step of glycosphingolipid synthesis.
Biochim. Biophys. Acta
1573
236-240
2002
1039689
Jennemann R.,Sandhoff R.,Wang S.,Kiss E.,Gretz N.,Zuliani C.,Martin-Villalba A.,Jaeger R.,Schorle H.,Kenzelmann M.,Bonrouhi M.,Wiegandt H.,Groene H.J.
Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth.
Proc. Natl. Acad. Sci. U.S.A.
102
12459-12464
2005
1039690
Jennemann R.,Sandhoff R.,Langbein L.,Kaden S.,Rothermel U.,Gallala H.,Sandhoff K.,Wiegandt H.,Groene H.J.
Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis.
J. Biol. Chem.
282
3083-3094
2007
1039691
Watanabe S.,Endo S.,Oshima E.,Hoshi T.,Higashi H.,Yamada K.,Tohyama K.,Yamashita T.,Hirabayashi Y.
Glycosphingolipid synthesis in cerebellar Purkinje neurons: roles in myelin formation and axonal homeostasis.
Glia
58
1197-1207
2010
1039692
Jennemann R.,Rothermel U.,Wang S.,Sandhoff R.,Kaden S.,Out R.,van Berkel T.J.,Aerts J.M.,Ghauharali K.,Sticht C.,Groene H.J.
Hepatic glycosphingolipid deficiency and liver function in mice.
Hepatology
51
1799-1809
2010
1039693
Jennemann R.,Kaden S.,Sandhoff R.,Nordstroem V.,Wang S.,Volz M.,Robine S.,Amen N.,Rothermel U.,Wiegandt H.,Groene H.J.
Glycosphingolipids are essential for intestinal endocytic function.
J. Biol. Chem.
287
32598-32616
2012
1039694
Amen N.,Mathow D.,Rabionet M.,Sandhoff R.,Langbein L.,Gretz N.,Jaeckel C.,Groene H.J.,Jennemann R.
Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing.
Hum. Mol. Genet.
22
4164-4179
2013
1039695
Nordstroem V.,Willershaeuser M.,Herzer S.,Rozman J.,von Bohlen Und Halbach O.,Meldner S.,Rothermel U.,Kaden S.,Roth F.C.,Waldeck C.,Gretz N.,de Angelis M.H.,Draguhn A.,Klingenspor M.,Groene H.J.,Jennemann R.
Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.
PLoS Biol.
11
0-0
2013
1039696
Rardin M.J.,Newman J.C.,Held J.M.,Cusack M.P.,Sorensen D.J.,Li B.,Schilling B.,Mooney S.D.,Kahn C.R.,Verdin E.,Gibson B.W.
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Proc. Natl. Acad. Sci. U.S.A.
110
6601-6606
2013
1039697
von Gerichten J.,Schlosser K.,Lamprecht D.,Morace I.,Eckhardt M.,Wachten D.,Jennemann R.,Groene H.J.,Mack M.,Sandhoff R.
Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals.
J. Lipid Res.
58
1247-1258
2017
1039698
Boer D.E.,Mirzaian M.,Ferraz M.J.,Zwiers K.C.,Baks M.V.,Hazeu M.D.,Ottenhoff R.,Marques A.R.A.,Meijer R.,Roos J.C.P.,Cox T.M.,Boot R.G.,Pannu N.,Overkleeft H.S.,Artola M.,Aerts J.M.
Human glucocerebrosidase mediates formation of xylosyl-cholesterol by beta-xylosidase and transxylosidase reactions.
J. Lipid Res.
62
100018-100018
2021
