Sequence of AMACR_RAT
EC Number:5.1.99.4
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA
General information:
Sequence
0 MALRGVRVLE LAGLAPGPFC GMILADFGAE VVLVDRLGSV NHPSHLARGK RSLALDLKRS
60 PGAAVLRRMC ARADVLLEPF RCGVMEKLQL GPETLRQDNP KLIYARLSGF GQSGIFSKVA
120 GHDINYVALS GVLSKIGRSG ENPYPPLNLL ADFGGGGLMC TLGILLALFE RTRSGLGQVI
180 DANMVEGTAY LSTFLWKTQA MGLWAQPRGQ NLLDGGAPFY TTYKTADGEF MAVGAIEPQF
240 YTLLLKGLGL ESEELPSQMS IEDWPEMKKK FADVFARKTK AEWCQIFDGT DACVTPVLTL
300 EEALHHQHNR ERGSFITDEE QHACPRPAPQ LSRTPAVPSA KRDPSVGEHT VEVLKDYGFS
360 QEEIHQLHSD RIIESNKLKA NL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
630573
Reichel C.,Brugger R.,Bang H.,Geisslinger G.,Brune K.
Molecular cloning and expression of a 2-arylpropionyl-coenzyme A epimerase: a key enzyme in the inversion metabolism of ibuprofen.
Mol. Pharmacol.
51
576-582
1997
630574
Schmitz W.,Helander H.M.,Hiltunen J.K.,Conzelmann E.
Molecular cloning of cDNA species for rat and mouse liver alpha-methylacyl-CoA racemases.
Biochem. J.
326
883-889
1997
630575
Kotti T.J.,Savolainen K.,Helander H.M.,Yagi A.,Novikov D.K.,Kalkkinen N.,Conzelmann E.,Hiltunen J.K.,Schmitz W.
In mouse alpha-methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes.
J. Biol. Chem.
275
20887-20895
2000
630576
Reichel C.,Bang H.,Brune K.,Geisslinger G.,Menzel S.
2-arylpropionyl-CoA epimerase: partial peptide sequences and tissue localization.
Biochem. Pharmacol.
50
1803-1806
1995
630577
Schmitz W.,Fingerhut R.,Conzelmann E.
Purification and properties of an alpha-methylacyl-CoA racemase from rat liver.
Eur. J. Biochem.
222
313-323
1994
630578
Schmitz W.,Albers C.,Fingerhut R.,Conzelmann E.
Purification and characterization of an alpha-methylacyl-CoA racemase from human liver.
Eur. J. Biochem.
231
815-822
1995
630579
Ferdinandusse S.,Denis S.,Ijlst L.,Dacremont G.,Waterham H.R.,Wanders R.J.
Subcellular localization and physiological role of alpha-methylacyl-CoA racemase.
J. Lipid Res.
41
1890-1896
2000
