EC Number   |
Protein Variants |
Reference |
|---|
    6.3.5.3 | F209W |
both the secondary structure content and activity of the mutant enzyme is very similar to the wild type protein |
728631 |
| 6.3.5.3 | H32A |
no synthesis of formylglycinamidine ribonucleotide detected |
672107 |
| 6.3.5.3 | H32Q |
no synthesis of formylglycinamidine ribonucleotide detected |
672107 |
| 6.3.5.3 | H72A |
mutant enzyme displays 1/20 of the wild type activity with a strongly increased Km for formylglycinamidine ribonucleotide |
672107 |
| 6.3.5.3 | H72Q |
mutant enzyme displayed 1/200 of the wild type activity |
672107 |
| 6.3.5.3 | L1181F |
the mutation causes a 60% loss in activity |
728631 |
| 6.3.5.3 | L1181W |
the mutant has secondary structure content and enzyme at par with the wild type protein and exhibits almost no destabilization |
728631 |
| 6.3.5.3 | L1181Y |
the mutation results in failure to yield soluble protein |
728631 |
| 6.3.5.3 | more |
identification of two natural T-DNA insertions lethal to the male gametophyte. The reproductive phenotype of hetererozygous plants carrying the pur4-2 mutated allele is more severe than that carrying the pur4-1 mutated allele, and pur4-2/+ plants show slightly delayed early development. The pur4-2 allele produces an antisense transcript and the amount of PUR4 mRNA is reduced in these plants |
694724 |
| 6.3.5.3 | more |
ORF75c-null viruses are unable to produce infectious virus, the protein may provide essential viral functions in addition to inducing promyelocytic leukemia nuclear body degradation |
693923 |
