EC Number |
Protein Variants |
Reference |
---|
4.2.3.17 | H579R |
accepts farnesyl diphosphate as substrate |
492239 |
4.2.3.17 | more |
a mutation Y841H, analogous to W753H mutation, can possibly lead to formation of verticillane |
747151 |
4.2.3.17 | more |
construction of truncation variant lacking the transit sequence and an additional 27 residues at the N-terminus, crystallization data |
716333 |
4.2.3.17 | W753H |
the mutation leads to the exclusive formation of side product cembrene A |
747151 |
4.2.3.17 | W753H |
the mutation leads to the exclusive formation of side product cembrene A. The simulations of the W753H mutant shows that, in the mutant structure, the His side chain is in the perfect position to deprotonate the cembrenyl cation en route to cembrene formation and that this abortive deprotonation is an energetically facile process |
747151 |