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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.126D115N the mutant exhibits a 7fold reduction in the value of kcat 714166
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.126E114Q the mutant shows a dramatic reduction in the value of kcat (2000fold) and a modest decrease in the value of KM (4fold) 714166
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.126E83A the mutant is essentially inactive, the mutant shows a very low, but measurable, level of activity with a kcat value that wis 10000fold lower than that of the wild type enzyme 714166
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