EC Number   |
Protein Variants |
Reference |
|---|
   3.6.4.13 | A115C/D262C |
site-directed mutagenesis, the mutant shows activity, structure and substrate specificity similar to the wild-type |
700979 |
| 3.6.4.13 | A115C/E224C |
site-directed mutagenesis, the mutant shows activity, structure and substrate specificity similar to the wild-type |
700979 |
| 3.6.4.13 | A115C/S229C |
site-directed mutagenesis, the mutant shows activity, structure and substrate specificity similar to the wild-type |
700979 |
| 3.6.4.13 | D172A |
the ration of (kcat/Km)ATP/(kcat/Km)GTP is 41% of the ratio determined for the wild-type enzyme |
713144 |
| 3.6.4.13 | D279A |
site-directed mutagenesis, the mutation affects ATP hydrolysis |
733632 |
| 3.6.4.13 | D310H |
site-directed mutagenesis of the V motif, leads to altered enzyme activity, overview |
698867 |
| 3.6.4.13 | D313H |
site-directed mutagenesis of the V motif, leads to altered enzyme activity, overview |
698867 |
| 3.6.4.13 | D755A |
site-directed mutagenesis, mutation in the conserved BMV 1a protein helicase motif, the mutant shows abolished RNA recruitment and RNA stabilization, and thus RNA replication function, but normal accumulation, localization, and 2apol recruitment, the mutant shows 90% reduced ATPase activity compared to the wild-type enzyme |
670083 |
| 3.6.4.13 | DELTA53-105 |
a region within the N-terminus of RHAU, referred to as the RSM, interacts with human telomerase RNA |
720599 |
| 3.6.4.13 | E168A |
site-directed mutagenesis, the mutation eliminates ATP hydrolysis and helicase activity, and the mutant is unable to restore PexsD-lacZ activity to levels observed with wild-type DeaD |
-, 757093 |
