EC Number   |
Protein Variants |
Reference |
|---|
   3.2.2.20 | D170N |
the mutation substantially decreases enzymatic activity without abolishing it |
732554 |
| 3.2.2.20 | D18A |
TAG mutant, prepared with QuikChange double-stranded mutagenesis kit |
646863 |
| 3.2.2.20 | E121A |
about 20% of wild-type activity |
750415 |
| 3.2.2.20 | E156A |
about 50% of wild-type activity |
750415 |
| 3.2.2.20 | E38A |
TAG mutant, prepared with QuikChange double-stranded mutagenesis kit |
646863 |
| 3.2.2.20 | H17A |
TAG mutant, prepared with QuikChange double-stranded mutagenesis kit |
646863 |
| 3.2.2.20 | I147V/T151A/A206S |
the mutant retains base excision activity toward alkylated DNA substrates, but its level of activity is decreased compared to the wild type |
732554 |
| 3.2.2.20 | K126N/E130G/N175D |
the mutant retains base excision activity toward alkylated DNA substrates, but its level of activity is decreased compared to the wild type |
732554 |
| 3.2.2.20 | L122M |
the mutant retains base excision activity toward alkylated DNA substrates, but its level of activity is decreased compared to the wild type |
732554 |
| 3.2.2.20 | more |
construction of a truncated DELTA80AAG enzyme mutant, substrate specificity in comparison to the wild-type enzyme shows that both the full-length and truncated AAG excise 1,N2-ethenoguanine, albeit weakly, from duplex DNA, while uracil is excised from both single- and double-stranded DNA, but only by full-length AAG, single-turnover excision kinetics, overview |
707488 |
