EC Number   |
Protein Variants |
Reference  |
|---|
    2.8.3.5 | more |
mutant with deletion of amino acid residues 249-254 shows no altered kinetic values |
645989 |
| 2.8.3.5 | C456F |
missense mutation derived from a SCOT-deficient patient, no enzyme activity |
645992 |
| 2.8.3.5 | T58M |
missense mutation derived from a SCOT-deficient patient, enzyme is functional |
645992 |
| 2.8.3.5 | V133E |
missense mutation derived from a SCOT-deficient patient, no enzyme activity |
645992 |
| 2.8.3.5 | DELTA249-254 |
delta-SCOT, deletion mutant, residues 249-254 are removed |
660636 |
| 2.8.3.5 | C456F |
no activity |
663018 |
| 2.8.3.5 | T435N |
retains significant residual SCOT activities |
663018 |
| 2.8.3.5 | V133E |
no activity |
663018 |
| 2.8.3.5 | C129S |
like wild-type SCOT rapid modification in the presence of acyl-CoA substrates |
672216 |
| 2.8.3.5 | C196S |
site-directed mutagenesis, the mutant protein is modified rapidly in the presence of acyl-CoA substrates in analogy to the wild-type enzyme |
672216 |
