EC Number   |
Protein Variants |
Reference |
|---|
    2.4.2.3 | C206_A207insGVPLC |
inactive and insoluble mutant protein |
658570 |
| 2.4.2.3 | C212S |
site-directed mutagenesis, the replacement has no significant effect on the loop (217-227 ARs) |
758663 |
| 2.4.2.3 | C212S |
the mutation accounts for the lower affinity of the mutant for inorganic phosphate, while the affinity for uridine remains unchanged |
-, 735375 |
| 2.4.2.3 | E196A |
complete loss of uridine phosphorylase activity |
659088 |
| 2.4.2.3 | E198D |
complete loss of uridine phosphorylase activity |
659088 |
| 2.4.2.3 | E198G |
complete loss of uridine phosphorylase activity |
659088 |
| 2.4.2.3 | E198Q |
complete loss of uridine phosphorylase activity |
659088 |
| 2.4.2.3 | E237K |
site-directed mutagenesis, the mutant enzyme shows reduced activity compared to the wild-type enzyme |
760136 |
| 2.4.2.3 | E248K |
site-directed mutagenesis, almost inactive mutant enzyme |
760136 |
| 2.4.2.3 | E79-E80insGVPLE |
inactive mutant protein |
658570 |
