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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.B77more engineering of truncated variant DELTAN123-GBD-CD2 for flavonoid glucoside diversification. Mutantions at residues W2135, F2136, F2163 and L2166 lead to improved promiscuity towards flavonoids including quercetin, luteolin, apigenin, morin, chrysin and naringenin -, 752238
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.B77more large-scale molecular dynamics simulations on truncated variant DELTAN123-GB-CD2 derived from the bifunctional DSR-E reveal a cooperativity of low frequency twisting, bending and wobbling modes leading to the movement of two blocks formed respectively by domains A and C and domains IV and V, and connected via the domain B which forms a flexible structural hinge. The catalytic pocket is surrounded by highly flexible loops that may play a key role in the acceptor promiscuity of DELTAN123-GBD-CD2 -, 751981
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