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EC Number
Protein Variants
Commentary
Reference
2.3.1.294
C171Q
the mutant mimics the acyl-enzyme intermediate
754094
2.3.1.294
R206G
the mutant shows a 10fold increase in kcat/Km when malonyl-CoA is varied at a fixed concentration of lauroyl-CoA (0.1 mM)
752750
2.3.1.294
T334A
phosphoablative mutant
-
,
755200
2.3.1.294
T334A/T336A
phosphoablative mutant
-
,
755200
2.3.1.294
T334D/T336D
the phosphomimetic mutant exhibits loss of acid-fast staining and is more susceptible to isoniazid, ethionamide and rifampicin compared to the wild type enzyme
-
,
755200
2.3.1.294
T336A
phosphoablative mutant
-
,
755200
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