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<< < Results 11 - 20 of 44 > >>
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4H291A site-directed mutagenesis, mutation of a alpha-subunit residue, highly reduced activity compared to the wild-type E1b component 656171
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4H291N site-directed mutagenesis, mutation of a alpha-subunit residue, highly reduced activity compared to the wild-type E1b component 656171
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4H291Q site-directed mutagenesis, mutation of a alpha-subunit residue, highly reduced activity compared to the wild-type E1b component 656171
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4H292A inactive enzyme, no binding of thiamine diphosphate 349090
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4more complete deletion of the bkdR open reading frame, produces fewer spores or the spores have reduced viability, is apparently not complemented in trans by the wild-type allele, is able to utilize leucine as sole carbon source and has no detectable growth defect, bkdR gene product acts as a repressor, rather than an activator of transcription 674248
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4more construction of transgenic Arabidopsis thaliana plants overexpressing the branched-chain alpha-keto acid dehydrogenase multienzyme complex BCKDC in chloroplasts via Agrobacterium tumefaciens transformation under control of the CaMV 35S promotor, accumulation of branched-chain acyl-CoAs and alteration of free amino acid composition in seeds, overview 657104
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4more enzyme complex regulation by reversible phosphorylation is impaired in component E1b S292 and S302 mutants, no or residual acylation of the lipoic acid-bearing domain of component E2b, overview 657370
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4more hE1b-Tyr113Phe mutant, specifically affects the decarboxylation reaction, thiamine diphosphate appears hyperactive, is prone to paracatalytic inactivation 677159
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4more missense mutation in E1b subunits that cause maple syrup urine disease: R114W-alpha, T166M-alpha, R220W-alpha. N222S-alpha. M64T-alpha. G204S-alpha. A208T-alpha. T265R-alpha, I281T-alpha, N126Y-beta, Q145K-alpha, H156R-beta, A209D-alpha, A240P-alpha. G245R-alpha, R252H-alpha, F364C-alpha, Y368C-alpha and Y393N-alpha 349040
Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.4more the hybrid E1b heterotetramer carrying one wild type, one S292Qalpha subunit, and two wild type beta subunits contains only one functional active site and exhibits nearly 40% of the wild type activity 687543
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